Infertility

no measureable follies

Why can't anything EVER EVER EVER go smoothly for me.  On day 6 of Stims and no measurable follies (one is 10.5mm but they don't count it unless its >11) but US tech said she saw ~4-5 little guys on each side.  My nurse said that they like to see at least some at this point but said that I very well could have a bunch that are close to being measurable....I hate this waiting game.  it is so very hard not to get down or give up but enough is enough.  I will endure because I want a baby more than anything in the world.....and truth is....I will never give up on that dream...even if I have to do 15 IVF cycles and go totally broke...it will all be worth it.  Thanks for letting me vent....anyone else go through a cycle where they were a slow starter?  And....I'm on max doses of follistem and menipur and also 5 mg lupron.  Not much else we can do but wait at this point 
TTC 2 years- Me and DH (28) with (severely) low sperm count- less than 40 total (last 2 SA showed only 5 and 6 sperm each)
IVF #1: ER 1/23/13- 4 eggs retrieved, 3 eggs fertilized; ET with 1 embryo 1/28/13 2 frosties beta #1 2/5 was 4.8- beta #2 2/7 3.5; BFN
FET #1- transferred one beautiful 4AA embie. Praying this is my take home baby. Beta 5/7/13- BFFN!!!
IVF #2: ER 7/17/13: 6R/3F- transferred 1 blast and 1 10 cell embryo 5dt.   Beta hell.  #1 2.5, #2 2.2- BFFFN! REALLY?
IVF #3: ER 12/1 and only 2 retrieved.  1 fertilized with ICSI.  Was planning on transferring one fresh and one frozen....fresh was only 14 cells at day 5...CANCELLED and devastated due to 5cm blood filled cyst in ovary and blood in uterus.
IVF #4: Antagonist protocol with endometrial scratch day one of stims.  ER 4/21: 6R/4M/3F- transferred 2 beautiful blasts (5dt) and one was hatching!  No frosties but hoping we won't need it!  Beta 5/4/14- 444(8dp5dt), Beta #2 10dp5dt 1002!  THIS HAS GOT TO BE IT!!!!!!!!!!  First US 5/15 we saw two of the most beautiful gestational and yolk sacs I have ever seen!  
****FINALLY PREGNANT WITH DI/DI TWINS!!!!!!!  

BRINLEY AND RILEY LONG.  Born November 20, 2014 at 32 wks 3 days.  4lbs7oz and 4lbs5oz.  1 month NICU time for "B's" and growing and feeding.  Now healthy, thriving, beautiful little girls!
 imagehttp://i62.tinypic.com/2dl9ap0.jpgpghttp://oi61.tinypic.com/o7t1y0.jpg

Re: no measureable follies

  • Hopefully your follicles get their act together.

    My only thought is why do they have you on lupron?  From what I've read, lupron can supress the ability of stims to stimulate follicle growth.  This is why after my poor response for IVF #1, I was switched to a conversion protocol.  I only took lupron until around my baseline and then switched to ganirelix, which is supposed to be better for poor responders. 

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    TTC #1 since August 2011

    My Blog

    September 2012: Start IF testing

    DH (32): SA is ok, slightly low morph, normal SCSA  Me (32): Slightly low progesterone, hostile CM, carrier for CF, Moderately high NKC, High TNFa, heterozyogous mutated Factor XIII, and +APA

    October 2012-May 2014: 4 failed IUIs, 3 failed IVFs, and 1 failed FETw/donor embryos

    November 2014: IVF w/ICSI #4 Agonist/Antagonist with EPP and Prednisone, Baby Aspirin, Lovenox, and IVIG for immune issues.  Converted to freeze all due to lining issues.  2 blasts frozen on day 6!

    January 2015: FET #2 Cancelled due to lining issues

    April 2015: FET #2.1


    PAIF/SAIF Welcome!

  • I was in a similar boat - sometimes it takes a little while to waken them up.  I hope you see some progress soon!

    My TTC Journey:
    Dx: Hypothalamic amenorrhea / mild PCOS (Pretty much a hormone/ovulatory disorder)
    Progesterone to induce period w/ the goal of Clomid - never got period (September 2011). Referred to RE.
    Femera - never responded to the meds (December 2011)
    Clomid with TI - BFN (February 2012)
    Injectables (Menopur) - hyperstimulated/canceled (March 2012)
    Injectables #2 (Menopur) with TI- BFN (May 2012)
    IVF - OHSS (transfer canceled), but 11 frozen! (June 1012)
    FET - 1 transferred on 8/09/12. Beta#1 (11dp5dt): 350.3; Beta#2: 365; Beta#3: 157. Biochemical pregnancy.
    FET # 2 - 1 transferred on 11/01/12. Beta#1 (11dp5dt): 337; Beta#2: 769. BFP!!! 1st ultrasound 11/28/12 showed heartbeat, but measuring 5 days behind. 2nd ultrasound 12/05/12 - miscarriage.
    FET # 3 - 1 transferred on 1/24/13. Beta#1 (11dp5dt): BFN.
    FET # 4 - 2 transferred on 3/21/13.  Bet #1 (11dp5dt): 660; Beta#2: 1,300.  Miscarried at home @ 6 weeks.

    FET # 5 - 2 transferred on 7/12/13.  Beta #1 (10dp6dt): BFN.
    Attempted an IUI in late August 2013, but didn't respond well.
    IVF #2 with PGS - Stims started 10/28 with retrieval on 11/11.  Of 14 mature eggs, 10 fertilized, 4 made it to Day 5 & 1 made it to Day 6. We did PGS on the Day 5 embryos, and 3 of 4 were normal. Had ET on 11/17. Beta #1 (8dp6dt): 203. Beta #2 (10dp6dt): 618. We since had two ultrasounds & on 12/19, our RE released us to the OB.  On 1/02/14, we had our first ultrasound with the OB where we heard the heartbeat.  We are so thankful for the blessing & crossing every finger & toe for a healthy & successful pregnancy.

    photo JuneBugs_IFbump.jpgimageimage

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  • FX your follies are gonna catch up soon.
    Me: 38
    DX:  Adenomyosis, Compounded MTHFR, PAI-1 4G variant

    DH: 34
    MFI due to Testicular Cancer

    Married March 2012 <3
    IVF w/ICSI #1
    10 little polar bears
    FET #1 with 2 polar bears ~Nov 6, 2013 BFN :(
    FET # 2 with 2 more polar bears ~March 19, 2014 BFP!!!
    Beta 1= 276
    Beta 2= 662
    4/19/14 ~ baby A became an angel
    5/02/14 ~ baby B became an angel
    5/3/14 ~ D&C
    FET #3 with 1 male polar bear ~October 3, 2014
    October 13, 2014 ~ BFN
    Fur Children:  Memphis 3y, Dutch 3y, Marcel 2y, Meadow 1y



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    January 2015 Siggy Challenge TTCAL
    Animals Interacting with Snow

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  • im sorry ur not seeing the progress you'd hoped for but FX the lil follies will catch up and you see great numbers on your next check!
    **SIGGY TICKER WARNING**
    Me: 27 High FSH (POF?) DH: 33 Slightly Low Morphology / Married Aug '08 TTC since 7/2009
    6 rounds of clomid = no luck
    IVF w/ ICSI & AZH #1 - Jan/2011 = ET cancelled OHSS
    FET #1 & #2 - March/2011 & June/2011 = Chemical Preg.
    IVF w/ Half ICSI #2 New RE - May/2012 = BFN!
    May '12 - Sep '13 - Took A Break
    Dec '13 IVF w/ Half ICSI #3!!!!! Switched RE
    Protocol - Lupron trigger/Follistim/Ganirelix/Estrace/Vivelle/Crinone
    12/27 - BFP! TWINS! EDD 9/3/14 ...Team PURPLE!
    6/27/14 - Emergency C/S @ 30w2d - Baby A 2lb 14oz, Baby B 2lb 11 oz
    image
    ALL WELCOME :)
  • Maybe talk to your nurse or RE today or tomorrow, if possible, about whether or not it would make sense to add Human Growth Hormone to the mix. It's not inexpensive ($800-1000), but if your RE thinks it could help those follies grow and get high quality eggs, it'd be worth it. It's no silver bullet, and may not even be something your RE would recommend for you or for this situation. My RE thought I'd only get 7 eggs, max. We added HGH after day 6 of stims and I got 17 (14 mature). Quality seemed decent too. No BFP, but we'll see how this FET works out. 

    Good luck!

    Began TTC #1 in Sept. 2010. I was 33, DH was 36.. Dx with DOR and slight MFI (8/4/11).

    Test results (after first RE visit 6/21/11): 7DPO b/w: Progesterone = 11.3; CD3 b/w: FSH = 10.1 mUnits/mL, E2= 52.0 pg/mL, AFC: 6; SIS Ultrasound: Uterus great, tubes clear! AMH: 0.3 

    IUI#1 June 2012 (Follistim/HCG trigger): BFN 
    IUI#2 July 2012 (Follistim/HCG trigger): BFN 
    IUI#3 August 2012 (Follistim/HCG trigger): CP (Beta #1: 4.61, Beta #2: 1.0) 
    IUI#4 October 2012 (Follistim, ovulated before trigger, missed IUI, converted to TI): BFN 
    Jan. 2013 New RE
    IVF #1 June 2013 MDL Protocol. Converted to IUI#4.1. (High E2 and 3+ mature follicles at first monitoring.) BFFN
    IVF #1.2 August 2013 Stop Lupron Protocol with Human Growth Hormone added. 17R, 14M, 9F (with ICSI), 2 embryos (decent quality - grade 2) transferred on day 3, 2 blasts made it to freeze. Beta 8/26. BFFN :'(

    FET #1 December 2013 Last try! Transferred 2 blasts -- graded 3AB and 4BB. Beta #1 (12/27/13) 530. Beta #2 (12/30/13) 1876. BFP! One bean. EDD 9/3/2014!

    We welcomed the most beautiful baby girl into the world on September 11, 2014!

    image

  • I was super slow my first IVF. They never changed my meds just monitored me very closely. I stimmed longer than they thought I would. I went today for my US and at day 6 (which I'm at too) they said they want to see them around 10mm. They told me the number can change a lot in just a few days. I'm going back Sunday for another US. Don't lose hope! I was right there with ya my first round and ended up with 10 at ER.
    2013- 2 IVF cycles with PGD to prevent genetic disorder from being passed on. Both BFFN :(
    2/2014 pregnant!  EDD 10/17/2014

    All always welcome! :)
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    BabyFruit Ticker
  • TaylorH84 said:

    I was super slow my first IVF. They never changed my meds just monitored me very closely. I stimmed longer than they thought I would. I went today for my US and at day 6 (which I'm at too) they said they want to see them around 10mm. They told me the number can change a lot in just a few days. I'm going back Sunday for another US. Don't lose hope! I was right there with ya my first round and ended up with 10 at ER.

    Cycle twins ;)

    Thanks everyone for helping ease my worries....I guess it is what it is hoping my major bloating means there is some serious follicle growth going on! Hehe!
    TTC 2 years- Me and DH (28) with (severely) low sperm count- less than 40 total (last 2 SA showed only 5 and 6 sperm each)
    IVF #1: ER 1/23/13- 4 eggs retrieved, 3 eggs fertilized; ET with 1 embryo 1/28/13 2 frosties beta #1 2/5 was 4.8- beta #2 2/7 3.5; BFN
    FET #1- transferred one beautiful 4AA embie. Praying this is my take home baby. Beta 5/7/13- BFFN!!!
    IVF #2: ER 7/17/13: 6R/3F- transferred 1 blast and 1 10 cell embryo 5dt.   Beta hell.  #1 2.5, #2 2.2- BFFFN! REALLY?
    IVF #3: ER 12/1 and only 2 retrieved.  1 fertilized with ICSI.  Was planning on transferring one fresh and one frozen....fresh was only 14 cells at day 5...CANCELLED and devastated due to 5cm blood filled cyst in ovary and blood in uterus.
    IVF #4: Antagonist protocol with endometrial scratch day one of stims.  ER 4/21: 6R/4M/3F- transferred 2 beautiful blasts (5dt) and one was hatching!  No frosties but hoping we won't need it!  Beta 5/4/14- 444(8dp5dt), Beta #2 10dp5dt 1002!  THIS HAS GOT TO BE IT!!!!!!!!!!  First US 5/15 we saw two of the most beautiful gestational and yolk sacs I have ever seen!  
    ****FINALLY PREGNANT WITH DI/DI TWINS!!!!!!!  

    BRINLEY AND RILEY LONG.  Born November 20, 2014 at 32 wks 3 days.  4lbs7oz and 4lbs5oz.  1 month NICU time for "B's" and growing and feeding.  Now healthy, thriving, beautiful little girls!
     imagehttp://i62.tinypic.com/2dl9ap0.jpgpghttp://oi61.tinypic.com/o7t1y0.jpg

  • Good luck with those follies, I am sure they will catch up.

    Me: 35  low AMH, normal FSH
    DH: 31 Fair DNA fragmentation test :( Normal SA
    TTC: since March 2012

    09-21-13 start IVF #1
    10-04-13 ER 6 eggs, 6 mature, all 6 fertilized. 3 frozen
    10-08-13 fresh transfer canceled due to high progesterone
    waiting for FET
    10-18 started BCP
    10-29 baseline appt scheduled
    11-20 scheduled date of FET #1
    12-2 BFN :(

    3-1-14 moving on to the next step. Switched RE. going to plan 3 IUI cycles while saving for IVF#2

    April 2014- IUI#1  BFN
    May 2014- IUI#2 BFN
    June 2014 IUI#3 BFN

    Taking a break for a while, focusing on our wedding.

    Sept 24th missed period! Surprise natural BFP
    10-15-14 first ultrasound
    06-05-15 EDD

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  • Just wanted you to know that I'm keeping my fingers crossed for you that things start to go so much smoother and those follies grow grow grow!
    TTC since May 2012
    Me: 32 H: 31
    DX: MFI-Very Low Count, I have Hashimotos.
    IVF prep September 2013 cancelled due to Ovarian Cyst
    IVF #1 October 2013 Antagonistic Protocol with ICSI  ER 10/31/13 (18R 16M 11F- 6 blasts to freeze)
    ET delayed due to OHSS 
    FET scheduled for July 8. Delayed due to a crazy high TSH (it had been under control for YEARS!)
    FET #1 8/5/14 sET BFN 

    All welcome!
  • I'm a slow grower too and just had ER after maxing out my RE's limit of 12 days of stims. The whole time they kept telling me that they want them to grow slowly. FX that you'll start to see something bigger soon!
    Pregnancy Ticker

    TTC #1 since June 2012
    Me (28) - DOR (AFC <10, undetectable AMH, >10 FSH), homozygous E429A MTHFR
    DH (29) - MFI low count and morphology

    September 2013 IUI#1 - Clomid + Trigger + IUI = BFN
    October 2013 IUI#2 - Letrozole + Menopur + Trigger + IUI = BFN

    Nov 2013 IVF/ICSI #1 - Protocol: BCP prep, high doses Menopur and Bravelle (12 days), ganirelex
    Results: 5 retrieved / mature, 4 fertilized, 1 arrested and 3 complex abnormal after day 3 PGS = Cancelled after ER
    Jan/Feb 2014 IVF/ICSI #2 - Protocol: Estrogen priming, high doses Menopur and Bravelle (11 days), microdose lupron
    Results: Cancelled after 11 days of stims due to low response and E2 levels
    Feb 2014 IVF/ICSI #3 - Protocol: No prep, low dose Menopur (6 days), ganirelex, Bravelle booster with trigger
    Results: 1 retrieved / 0 mature = Cancelled after ER

    Officially moving on to embryo adoption! We used and love Embryo Adoption Services of Cedar Park
    October 2014 FET #1 - BCP/Lupron/Estrace/Prometrium, transferred 2 of 4 from match #1, BFN
    December 2014 FET #2 - BCP/Lupron/Estrace/Prometrium, transferred 2 of 4 from match #1, BFN
    March 2015 FET #3 - BCP/Lupron/Estrace/Prometrium, transferred 2 of 6 from match #2, BFN
    May 2015 FET #4 - BCP/Lupron/Estrace/Prometrium, lost 2 to thaw, transferred 2 of 6 from match #2, BFN
    October 2015 FET #5 - Natural cycle, lost 1 from match #3 and 1 from clinic backup to thaw, transferred 1 backup, BFN
    February 2016 FET #6 - Natural cycle, transferred 1 from match #4, B FREAKING P!
    Beta 1 = 162, Beta 2 = 316, doubling just over 48 hours

     

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