Intro — The Bump
TTC after 35

Intro

Hi - 

I just got a BFN on my 3rd Clomid + Ovidrel Shot + TI + IUI.  My RE had said if after 3 it doesn't work, then we need to move to IVF.  So we are taking this cycle 'off' from a medication/hormone perspective (still will try on our own) and will start IVF the next cycle.  I also started acupuncture this past cycle and will continue since I am willing to try anything that works at this point.  I have an appt next Tues and they will give me the full schedule, etc at that time.  

Background: I just turned 36, husband is 38. Been married 3+ years.  TTC since Mar 2012, with a 3 month break when I took a new job last summer.  Started testing, etc in June.  So far, nothing has come up as to why we are not pregnant, so I guess that makes us unexplained - which is more frustrating.

Really hoping we manage to get pregnant this cycle on our own.  Any advice on how to prepare for what is next is greatly appreciated.

Good luck to everyone here
***signature/ticker warning***
Me:37 DH:39
TTC#1 since 3/2012

Diagnosis : Unexplained Infertility

3 BFN rounds Clomid + IUI
IVF 1 - BFN, 1 Frozen
IVF 2 - BFN, 5 Frozen
FET 1 - BFP!!! EDD 1/24/15 Beta 1: 700, Beta 2: 2,156; 1st U/S 6w3d: HB 118bpm, 2nd U/S 9w3d: HB 171bpm

imageimageimage
Pregnancy Ticker

Re: Intro

  • Going from Clomid  straight to IVF seems like a big jump... what about an injectible IUI cycle... the success rate is much higher than Clomid.
    ***siggy/ticker warning***

    Me:36 DH:38 TTC#1 since 4/2012
    Me DX: Hashimotos,Hypothyroid, DOR, MTHFR,  DH: normal

     IUI #1-#4 BFNs and a few cancelled cycles in the mix.
    - poor responder
    ***Suprise BFP on 6/13/13. Natural MC @6wks 3days
    IVF#1 and 2- Cancelled due to no response on max stimms
    FET 5/20- BFP
    1st Beta- 641
    2nd beta- 2166
    Sono- TWINS!!!!
    Two Boys! Born January 2015 @36 weeks.  Healthy and no NICU!  So blessed!



    image 

  • Hi - yeah - I have heard someone else ask that - but the 3 Clomid IUIs were using a Trigger Shot to induce ovulation - so is that what you mean by injectibles?

    I did get 2 mature follicles on 2 cycles, and 3 on my first.  My RE said since I was responding to the clomid, and they were already doing trigger, there was no need to continue (since it isn't working) and that the next route was IVF.  

    I have an appointment next Tuesday and will ask what they do for injects cycles at that time.  

    Any info is appreciated!

    ***signature/ticker warning***
    Me:37 DH:39
    TTC#1 since 3/2012

    Diagnosis : Unexplained Infertility

    3 BFN rounds Clomid + IUI
    IVF 1 - BFN, 1 Frozen
    IVF 2 - BFN, 5 Frozen
    FET 1 - BFP!!! EDD 1/24/15 Beta 1: 700, Beta 2: 2,156; 1st U/S 6w3d: HB 118bpm, 2nd U/S 9w3d: HB 171bpm

    imageimageimage
    Pregnancy Ticker
  • Loading the player...
  • Welcome aboard!  I'm new here myself.  I'm so sorry none of the IUIs worked out.  We are also "unexplained" infertility and it can be really frustrating.  I completely understand.

    I agree with the PP, that is a huge leap from Clomid to IVF.  Is there any reason why your RE wants to be so aggressive?


  • Hi @Maellen  I am sorry you are finding yourself here as well.  Unexplained is definitely very frustrating.

    I am very confused since I guess I thought I was doing injectibles since I was using a HCG shot (ovidrel) with the Clomid and IUI. Is there something else that is called injectibles?

    At any rate, I do trust my RE - she has a very good reputation and good outcomes.  She came highly recommended from my gyn and others. So if she says IVF is next, then we are ok with that - as I know everyone else here feels - whatever it takes to get pregnant and have a baby sooner rather than later. 

    Hope your stay here is brief


    ***signature/ticker warning***
    Me:37 DH:39
    TTC#1 since 3/2012

    Diagnosis : Unexplained Infertility

    3 BFN rounds Clomid + IUI
    IVF 1 - BFN, 1 Frozen
    IVF 2 - BFN, 5 Frozen
    FET 1 - BFP!!! EDD 1/24/15 Beta 1: 700, Beta 2: 2,156; 1st U/S 6w3d: HB 118bpm, 2nd U/S 9w3d: HB 171bpm

    imageimageimage
    Pregnancy Ticker
  • I'm new to all of this and don't have any experience other than TTCAL on our own. GL and I hope you find some answers.

    image

    Me: 38, DH: 40 | Married April 2012 | TTC since October 2012  

    DX: Hypothyroid, DOR, Right Tube Blocked, Uterine Fibroid (awaiting hysteroscopy) | DH: Beta Thal Minor, ED (Cialis)

    OCT - DEC 2012 | TI | BFN

    JAN 2013 | BFP ~ EDD 9/23/13

    MAR 2013 | MMC due to Trisomy 10 ~ D&E MAR. 8

    APR - JUN 2013 | TTA

    JUL - NOV 2013 | TI |  BFN

    NOV 2013 | HSG & SHG ~ Right Tube Blocked & "Thickening" of Uterus

    DEC 2013 - JAN 2014 | NTNP |  BFN ~ Switched to new practice

    JAN - FEB 2014 | 3-D u/s & SHG ~ Uterine Fibroid ~ Awaiting Hysteroscopy

    ***All Are Welcome!***

    image   image  image

  • *** TICKER WARNING ***

    My RE had the same plan for us: he recommended aggressive Clomid cycles (meaning Clomid with an Ovidrel trigger shot) and if that didn't work, that we should move on to IVF. His logic was success rates not improving for multiple IUIs combined with our age (I was 36 when we first met with him).

    When I asked about an injectable cycle (which I took to mean other medications than Clomid and Ovidrel--a quick search says they're Gonadotropins), he said that the success rates were not dramatically different. YMMV based on your specific case. I was responding very well to Clomid; our diagnosis was unexplained IF. Friends of ours did not have any success with Clomid, but have had multiple successes with injectable cycles (not sure if they did TI or IUI--she's younger than I am).

    FWIW, we wound up getting pregnant during a break between medicated cycles. The body is weird and frustrating.  

    AMA & SAIF. TTC #1 since Oct. 2010. DX: Unexplained. BFP on break after 32 months trying and 2 med cycles. Baby girl born at 40w0d!

    Baby Birthday Ticker Tickerimage

    jbelle

  • @jbelle - thanks for the explanation.

    Yes, our RE said that essentially the outcomes rates would be essentially the same as with IUI / Clomid/Ovidrel.  Hence moving to IVF.  And the fact that I am 36, I am sure influences the next steps.

    And congrats on getting BFP in between cycles (the same actually happened to a close friend of mine) so who knows - maybe on this cycle when we are 'on our own' things will work!  Wishing you all the best as you continue through the next few months!
    ***signature/ticker warning***
    Me:37 DH:39
    TTC#1 since 3/2012

    Diagnosis : Unexplained Infertility

    3 BFN rounds Clomid + IUI
    IVF 1 - BFN, 1 Frozen
    IVF 2 - BFN, 5 Frozen
    FET 1 - BFP!!! EDD 1/24/15 Beta 1: 700, Beta 2: 2,156; 1st U/S 6w3d: HB 118bpm, 2nd U/S 9w3d: HB 171bpm

    imageimageimage
    Pregnancy Ticker
  • Hi ladies injectible IUI's are usually when meds are all through injections, the "trigger" sometimes ovidrel sometimes something else is also an injection but not generally consider "the injectible IUI".

    I wish  you all the best good luck!

    image
    My Ovulation Chart



    Me: 41 DH: 46. We are TTC our 1st, started July '11,
    3 cycles clomid with Ob,
    1 cycle Tamoxifen with Ob,
    Diagnosed PCOS 11/5/12
    clomid, trigger & timed bd 12/12 BFN
    1st clomid IUI 1/4/13 BFN.
    2nd clomid IUI 2/13 cancelled didn't respond to clomid.
    3/15/13 scheduled laparoscopy & on bcp.

    May 10 IUI from injectibles - BFN 

    May 22 done with interventions it will either happen or it won't. 

    February 2014 No longer actively trying, but not preventing. 

    SURPISE BFP 4/2/2015!!!!!!!!!!

    Miscarriage 4/23/15

     

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