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Ok... Lets talk Heprin?

Lacyj67Lacyj67 member
in Infertility Veterans
So had a talk with my RE on the phone this morning and he found some interesting things with some of my blood work we did last wed. He said I have some blood clotting issues which are inherited by our parents. He said I will most likely need to be on Heprin as of next transfer. He said alot of long dr words I didn't understand and wanted to know if any of you know it have used Heprin during your pregnancy?
Me 34 and DH 39 married in aug. 2002
Did 5 round of clomid 2010 =BFN
 High levels of NK CELLS DX sept.2012 DOR:# 0.02 
IVF #1 May 2012  ER 4, EF 2, ET 2 =BFN
MINI IVF Oct.2012  Cancelled 10-27-12
Ivf #3 Antagonist Protocol April 2013
Shared cycle..Donor cycled in July Got 12 eggs 9 fertilized and 8 frozen!!
DE FET #1 Sept. 3rd 2013 FIRST BFP EVER 5dp5dt
miscarried Sept 24th at 5 weeks 5 days
Etopic  D&C and hysterscopy Nov 5 2013
dx with pre genetic blood clotting dec 2013
FET #2 Jan 31st  2014 
Miscarried for a second time again at 5 weeks 5 days
Currently fostering to adopt an amazing little 1 year old boy..P.J!
FET#3  is Oct 29th 2014
BFN on fet #3
Last and FINAL FET coming JAN 28th 2015
Everyone Welcome






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Re: Ok... Lets talk Heprin?

  • luvbostonluvboston member
    Anti phospholipid antibody syndrome
    That's what I used it for other ppl use it for Antiphosphotidylserine
    Antithrombin III
    Prothrombin II mutation
    Protein C activity
    Protein S activity
    Factor V Leiden

    Pai you would be on baby aspirin
    6 m/c
    Anovulatory cycles, increased Synthroid Diagnosed Sep 2010
    Natural cycle Dec 2010 BFP M/C 6 1/2 Weeks, D&E Jan 2011
    1 Clomid/Ovidrel BFN May 2011
    Natural cycle Aug 2011 BFP M/C 4 Weeks
    1 IUI Sept 2011 BFP M/c 7 weeks
    Provera Dec 2011 BFP M/C 3 Weeks
    DQ ALPHA HLA MATCH, High NK Cells Diagnosed Dec 2011
    IVF March 2012 BFP m/c 4weeks 5 days (IL, Prednisone)
    IVF#2w/DS July 2012 MEGA FAILURE BFN (IL, Dexamethasone)
    Diagnosed No real HLA Match, DQ Beta Triad, High TNF, Low NK Cells
    Oct 2012 Natural Cycle m/c 4wks (Lovenox, Prednisone) 
    Went to Beer Center- high tnf, low lad, implantation failure
    Nov/Dec 2012 LIT Treatment
    Dec 12 Humira
    Jan 2013 BFP
    Humira,LIT,Prednisone, Lovenox, IVIG, Baby Aspirin
    Miracle Born August 2013 Premature

    Yours doesn't have to be a sad story


    image
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    Lilypie - (ugiy)


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  • poohnikipoohniki member
    I don't know too much about it but that is what I am looking into as well. It appears baby aspirin, lovenox or heparin are commonly prescribed blood thinners during IVF cycles.
    ***WARNING***

    TTC Since 12/2008;  DH: 32, Azoospermia     me: 33, DX during IVF #4: Low AMH (Normal FSH) / SER due 
    to IVF Meds (causing failure to fertilize) Recent DX: Hashimoto's, Lupus Anticoagulant, White Blood Cell Disorder 
    High ANA, ATA, & APA, PAI-1 Heterozygous= blood clotting disorder; connective tissue disorder 
    IVF w/ ICSI #1 2/2011     IVF w/ ICSI #2 5/2011    IVF w/ ICSI #3 12/2012   *New RE* IVF w/ ICSI #4  5/2013
    IVF w/ ICSI #5 8/2013 (Natural Cycle- No drugs)- One follicle->one blast. CCS normal. FET 9/10- 6BB blast. m/c @ 5w
    IUI #1 12/23- BFN  IUI #2 Cancelled (ovulated during AF)  Prep:CoQ10 (300 mg); DHEA (25 mg); Melatonin (3 mg), Folgard 2.2, Metformin 500 2x, Levothyroxine 50mcg, Aspirin 81mg w/ calcium, B12,  Vit. D 4000 & Prenate Elite Daily; Cabergoline 1/2 pill 2x week-  Cycling: Estrace Priming; Prednisone 10mg, Lovenox 40mg 2x,  Femera & Menopur   
    IUI #2.1 6/30 & 7/1. 1st Beta: 90 (7/15); 2nd Beta: 226 (7/17); 3rd Beta: 766   EDD: 3/23/2015

       **ALL WELCOME**                                    My Blog 
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    image


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  • Lacyj67Lacyj67 member
    I've been on baby asprin for a long time now.... So I imagine that will continue but guess we will add in the Heprin as well.
    Me 34 and DH 39 married in aug. 2002
    Did 5 round of clomid 2010 =BFN
     High levels of NK CELLS DX sept.2012 DOR:# 0.02 
    IVF #1 May 2012  ER 4, EF 2, ET 2 =BFN
    MINI IVF Oct.2012  Cancelled 10-27-12
    Ivf #3 Antagonist Protocol April 2013
    Shared cycle..Donor cycled in July Got 12 eggs 9 fertilized and 8 frozen!!
    DE FET #1 Sept. 3rd 2013 FIRST BFP EVER 5dp5dt
    miscarried Sept 24th at 5 weeks 5 days
    Etopic  D&C and hysterscopy Nov 5 2013
    dx with pre genetic blood clotting dec 2013
    FET #2 Jan 31st  2014 
    Miscarried for a second time again at 5 weeks 5 days
    Currently fostering to adopt an amazing little 1 year old boy..P.J!
    FET#3  is Oct 29th 2014
    BFN on fet #3
    Last and FINAL FET coming JAN 28th 2015
    Everyone Welcome






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  • megs3084megs3084 member
    Typically I'm on lovenox and baby aspirin cept they're on hold cause of my bleeding. The plan is to keep me on lovenox until 32-34 weeks then switch to heparin in case I deliver earlier than planned. I'm high pai1, APA. Plus we use the lovenox to help my restricted uterine blood flow. I started it around day3-4 of stims I believe.
    "Everything will be alright in the end. So if it's not alright, it is not yet the end."
    Me:29 DH:29  TTC since 1/11 Dx: unexplained IF/early DOR/immune issues 
    Feb'12- July'12-testing(all clear minus slight arcuate ute), 3 IUI with clomid all BFN
    8/30IVF#1 Antagonist protocol- ER 9/11-8R, 7M, 5F. 
    ET 9/14 2 embies transferred. 1 10cell Grade 4, 1 8cell Grade 4. No frosties. BFN
    IVF#2 Antagonist protocol plus baby aspirin- ER 12/5-16R, 12M, 8F!
    ET 12/10 5dt! 1 fully expanded blast & 1 early blast. No frosties. BFN
    3/13 hysteroscopy & polypectomy, Consulted w Dr. Kwak-Kim.  
    DX: High NK cells, cytokines, DHEAs& PAI1;  hypothyroid, +APA, restricted bloodflow
    7/13 IVF#3 Long lupron protocol with PIO, Crinone, Prometrium, and vivelle
    (plus synthroid, metformin, baby asa, metanx, PNV, Vit E, D, calcium, fish oil, CoQ10, IVIg infusions and lovenox per Dr. Kwak-kim)
    ER 7/19 14R, 11M, 9F(4 natural fert, 5 with ICSI)
    ET 5dt 7/24 2 fully expanded blasts.  SURPRISE 3 FROSTIES!!!
    Beta #1 8/2 335!!!! Beta #2 829!!!  1st u/s 8/14 showed TWINS!!!!!
    11/11: TEAM PURPLE!!!!!
    3/21/14-L&W born at 37w via csection
    Here Comes the Sun Blog
    PAIF/SAIF welcome!
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