Trouble TTC

estrogen dropping during stims?

Any IVF ladies have any insight into e2 levels dropping during stims? Is it normal on ganirelix? I've read some stating that on google but others with stories of getting cancelled from it. Wednesday my e2 level was 1108 and then I started the ganirelix and next day it was 860 and today its 803. Hoping it raises tomorrow but looking for any "yes this is normal" stories.

I'd ask the IF board but don't want to flood them with questions since I'm new over there where as here you all know me and there is enough of a cross over from boards I thought I'd still get some answers.

post and run as I try to get some sleep before my 530 alarm in order to drive to appointment hour away tomorrow.

TTC since July 2009. Dx MFI & LPD. 
IUI#1&2&3 (2011 & 2012) BFN
IUI#4 1/23/13 on 75iu x9 Follistim = BFP then chem preg m/c (Feb 2013)
IUI#5 BFN (April 2013)
IVF w/ICSI Oct. 2, 2012 - 13R, 11M, 7F, 1 frozen blast 4BB grade - - - FET Nov 15, 2013
BFP! Beta 1:104 @ 10dp6dt, Beta 2:178 @ 12dp6dt,  beta 3:366 @ 14dp6dt
Saw heartbeat twice before missed M/C at 8w3d on 12/27/13, missing my little angel boy
JUNE 2014 IVF#2;  5R, 2M, 1F Three day transfer 6/7.  Beta 6/18 - BFN
Child Free Now?
S/PAIFW , S/PALW

My Blog

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Re: estrogen dropping during stims?

  • I don't have a concrete answer for you, Katib, but am hoping for the best for you! I took Cetrotide with my last inject cycle (and will take it again with this IVF cycle) and I think it's the same principle as ganirelix. Unfortunately for me, my E2 still went up and I over responded so IUI#4 was canceled. It sounds like your meds are doing their job, so hopefully your smaller follies can catch up and you'll get lots of eggs at ER. I'm rooting for you!!!
    **SIGGY WARNING**

    Me: 32 DH: 35  TTC#1 since March 2012
    Dx: Poor Embryo Quality, Arcuate Uterus, Poor Uterine Blood Flow, Mild Endo, 
           Protein S Deficiency, Sjorgen's Syndrome 

    IUI #1-5: BFN
    Laparoscopy & Hysteroscopy: minimal endo, partial septoplasty
    IVF #1: 10R/6M/6F ~ Day 3 ET = BFN
    IVF #2: 14R/9M/5F ~ transfer canceled ~ all embryos arrested at 1-2 cell stage
    IVF #3: 9R/5M/5F ~ 1 frosty!
    IVF #4 (FET #1): BFN

    IVF #5 (DE IVF #1 with Dr. KK protocol): Currently PREGNANT!!!!!!
    Synthroid + Prednisone + Metformin + Baby Aspirin + Supplements Galore = 15+ pills a day
    Lupron + Lovenox + Delestrogen + IVIG + B/W = 2-5 pokes a day
    19R, 17M, 17F - transferred two Grade A blasts 11/16, four frosties!!!
    Beta #1 11/24 (13dpo/8dp5dt) = 367 ~ Beta #2 11/26 (15dpo/10dp5dt) = 709
    Beta #3 11/29 (18dpo/13dp5dt) = 1,997 ~ Beta #4 12/1 (20dpo/15dp5dt) = 3,403

    imageimageimage

    My Blog: Running and Dreaming for Two ~ All are Welcome!
  • I know it's supposed to suppress LH to keep you from ovulating but thr estrogen not going up os just concerning. FX todays BW shows some increase.

    TTC since July 2009. Dx MFI & LPD. 
    IUI#1&2&3 (2011 & 2012) BFN
    IUI#4 1/23/13 on 75iu x9 Follistim = BFP then chem preg m/c (Feb 2013)
    IUI#5 BFN (April 2013)
    IVF w/ICSI Oct. 2, 2012 - 13R, 11M, 7F, 1 frozen blast 4BB grade - - - FET Nov 15, 2013
    BFP! Beta 1:104 @ 10dp6dt, Beta 2:178 @ 12dp6dt,  beta 3:366 @ 14dp6dt
    Saw heartbeat twice before missed M/C at 8w3d on 12/27/13, missing my little angel boy
    JUNE 2014 IVF#2;  5R, 2M, 1F Three day transfer 6/7.  Beta 6/18 - BFN
    Child Free Now?
    S/PAIFW , S/PALW

    My Blog

    image



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  • Yay!  Estrogen finally went back up!  It's 1199 this morning and I'm allowed to skip monitoring tomorrow so I assume I will trigger Monday for Wednesday ER.  

    TTC since July 2009. Dx MFI & LPD. 
    IUI#1&2&3 (2011 & 2012) BFN
    IUI#4 1/23/13 on 75iu x9 Follistim = BFP then chem preg m/c (Feb 2013)
    IUI#5 BFN (April 2013)
    IVF w/ICSI Oct. 2, 2012 - 13R, 11M, 7F, 1 frozen blast 4BB grade - - - FET Nov 15, 2013
    BFP! Beta 1:104 @ 10dp6dt, Beta 2:178 @ 12dp6dt,  beta 3:366 @ 14dp6dt
    Saw heartbeat twice before missed M/C at 8w3d on 12/27/13, missing my little angel boy
    JUNE 2014 IVF#2;  5R, 2M, 1F Three day transfer 6/7.  Beta 6/18 - BFN
    Child Free Now?
    S/PAIFW , S/PALW

    My Blog

    image



  • good luck Katib!  I'm sure you're excited :)
    Baby Birthday Ticker Ticker

    Mama to Three Girls: 
    Twins born March 2014 at 26 weeks due to preterm labor
    and our 37weeker born May 9th, 2016!






  • Good luck Katib!!!!!
    My Ovulation Chart
    TTC since 0ct. 2011
    Me-34,DH-34
    Dx:Hypothyroidism 2008
    HSG- All clear CD 3 bloodwork normal
    SA- Abnormal Dx:MFI
    DH on 50mg Clomid 3x week
    BFP#1- 1/21/13 CP 1/24/13
    Cycle 18,19 & 20 50mg Clomid+trigger+IUI= All BFFN
    Cycle 21-25 Taking a break for now, still HIO Hoping!
    Moving onto IVF Next AF
    (PAIF/SAIF Welcome)
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