Beta = Fail
ksfrye
member
A year ago today, I had a miscarriage. Now, I also get to remember it as the day my IVF #1 was a BFN! I'm crushed! I just don't understand how this happened when everything looked so good. The embryologist said my two blasts were perfect!. She even said with my age that my risk of multiples would be really high and I should be prepared for that. Now I have nothing but a bruised stomach and a depleted savings account. But I've decided I'm done crying about it. Crying isn't going to make me pregnant. We are scheduled to meet with my RE next Thursday and I'm interested to see what he'll have to say. Then DH and I can plan what to do next.
The light at the end of our tunnel is we have 1 frostie waiting for us. Which leads me to a question? The embryologist told me that 50% of all frozen embros survive the thaw. Has anyone heard of that? Does the percent sound correct?
Me: 29, Mild DOR
DH: 31, SE mostly normal, 1st SE morph 5%, 2nd SE morph 15%...yeah!.
BFP July 2011, Natural MC August 2011.
3 cycles of 50mg Clomid = BFN
*New RE* Feb/Mar 2012 100 mg Clomid + Trigger + IUI = BFN
*3rd RE* April-June -Break Cycles begin prep for IVF by doing 2 Heparin injects daily....fun fun!
IVF #1 - ER 7/19, ET 7/24, 2 beautiful embies transferred. Beta 8/2 = BFN
*New RE...yes again* FET Nov 2012 with our lone ranger = BFFN
RE Suggests Trying IUI Again, Jan. 2013 IUI #2 =BFN
Feb. 2013 IUI #3 = BFP!!!, Beta #1 (15dpIUI) = 90, Beta #2 (17dpIUI) = 210, U/S Scheduled for 3/18
Re: Beta = Fail
((hugs)) BFNs are always so hard.
We have had a very poor thaw rate, but I know that we are a rare case. I would say 50% is erring on the side of caution. Good luck with your FET. They are much easier than a fresh.
************ Signature/Ticker Warning ************
Me (32) DH (36) - Finding our way to baby #1
Me: POF/DOR - AMH <0.16, heterozygous c677t MTHFR, insulin resistant and gluten intolerant
DH: Severe MFI
12/2/11 - IUI #1- BFN
8/1/12 - IVF #1 - Zero response from max stims (600iu intramuscularly)
My ovaries are just for decoration
12/6/12 - Adopted five embryos that had been frozen for over ten years!
2/11/13 - DEmbryo FET #1 Thawed four, sadly two didn't survive. Transferred two beautiful blasts.
2/16/13 - First BFP of my life @ 6dp5dt! EDD 10/30/13
3/27/13 - After beta and u/s hell, no heartbeat ever detected. D&C at 9w1d.
6/5/13 - Adopted four new embryos that had been frozen for seven years!
9/12/13 - DEmbryo FET #2. Thawed and transferred two beautiful blasts
9/17/13 - BFP @ 5dp6dt! EDD 05/31/14
9/29/13 - m/c @ 5w1d.
11/19/13 - DEmbryo FET #3. Thawed and transferred one blast from each batch. Wow!
11/23/13 - BFP @ 4dp6dt! EDD 8/7/13
Beta #1 @ 13dp6dt - 522 Beta #2 @ 16dp6dt - 1373
6w5d ultrasound showed one perfect baby with a beautiful heartbeat of 134bpm!
Snowflake baby is a girl!
Our beautiful Snowflake girl arrived on July 22, 2014!
My embryo adoption blog: Wishing on a Snowflake
TTC since Sept 2009, 2 uterine septum surgeries (Jan and March 2011), 1 chemical pregnancy (4/11), 1 ectopic pregnancy (8/11), and missed m/c at 11w5d (3/12)
Failed IVF #1 (July 2012)
FET #1 October/November 2012 BFP, m/c at 5 3/7
February - operative hysteroscopy
Late April/May FET #2
<img src=
I'm so sorry. It's hard to not have IVF#1 work when you have so much invested.
I think 50% sounds low for thaw rate. In recent years, advanced labs began using vitrification for frozen embryos. The thaw rate for vitrified embryos is closer to 90% so you should see how yours were frozen, if you don't know already. FWIW, the embryologist told us that our two looked better after thawing than they did in the pics from before they were frozen.
Make a pregnancy ticker
Oh ksfrye, I am SO sorry. The only thing worse than bad news is more bad news. Its a terrible day, and I hope you can have a good cry. You deserve that (and OH so much more!) The bruised soul, the bruised savings, the bruised body... its just awful. I hope that your doctor has some ideas for you at you WTF next Thursday.
Its great that you have a frostie there. 50% sounds very cautious on his part. I think that the thaw rate is a good bit higher, but I am not so studied on that. I've never had one.
With such perfect blasts, it still does happen that they are not sound enough to survive. Doctors only know what they can see for the 5 days they have the embryos. Perhaps he will order some karotype testing before FET. I am curious to know what he has to say.
Sending you lots of strength, and I hope you and your husband can find a way to heal and move ahead. Hugs.
TTC#1 since October 2010
"The jump is so frightening between where I am and where I want to be...because of all I may become I will close my eyes and leap." Mary Anne Radmacher
Me:35, 5 major abdominal surgeries for Ulcerative colitis, failed j pouch, perm. Ileostomy DX-DOR & Tubal abnormalities/Extensive Adhesions from earlier surgeries.latest fsh -26
IVF 1- March 2012 Antagonist Protocol; BCP until March 3; AFC this cycle is 10 (Hooray); Start stims on March 9; ER on March 19- 2R; 2T (1 perfect 8 cell, 1 scrappy 3 cell); tubal infection from ER-hospitalized. Doomed! BFN
Essure Procedure to treat bilateral hydrosalpinx; June 2012, wait 3 months for confirmation test.
IVF2 (Egg Banking)-letrozole/antagonist cycle; June/July 2012 225iu merional + cetrotide; slow responder, Ovulated before ER. Unbelievable. Canceled remaining cycles with my eggs
DE IVF in Brno, Czech. Approx. ET on Oct 6 CANCELLED-Essure didn't close both tubes-test again in 3 months
IVF3-DE IVF ET on Dec 9, 2012 (decided to roll the dice no matter what!)
2 perfect HB transferred; 8dp5dt beta:36; 10dp5dt beta 15; chemical pregnancy.
Turning our hearts toward adoption
DH:36, SA-perfect
Married since July 11, 2009
Fur baby Cairn Terrier
SAIF/PAIF Welcome
TTC since 5/2010
DX with Diminished Ovarian Reserve - AMH of 1.1 - 7/2011; AMH of .42 8/2012BFP 9/1/10-M/C confirmed 9/8/10-Methotrexate 10/6/10
IUI #1 (w/clomid)-9/5/11-BFN ; IUI #2 (w/clomid)-10/5/11 - BFP - 11/1/12-No sac seen; 11/2/11 and 11/9/11-Methotrexate
IVF #1- ER 2/2; ET 2/5;-Two 8 cell embryos transfered = BFFN
Surprise BFP - 5/7/12
U/S on 6/8/12 - H/B at 128 BPM; U/S on 6/14/12 @ 9wks-No H/B-D&C on 6/17/12
IVF 2.0- ER 10/17; ET 10/20-One 12 cell, one 10 cell and one 8 cell embryo transfered
BFP! 11/16/12 U/S- Two nuggets with perfect heartbeats! EDD 7/10/13
5/31/2013- My miracles arrived at 34w2d! Welcome to the world Harper and Nolan!
My Blog- http://waitingonaangel.wordpress.com/
DX: DH (30) severe MFI, severely low count & low motility
Me (32): all clear
Appt with Urologist 5/21/12: exam, ultrasound, bloodwork all normal.
Testicular Biopsy with TESE on 6/8/12. good sperm found! (left side only) froze sperm, failed thaw test
Orientation for IVF/ICSI on 6/13/12. Waiting for the green light following biopsy results...results show adequate sperm production both sides.
2nd SA 6/18/12: sample is "adequate for ICSI"
Plan: IVF/ICSI July 2012!
ER: 7/26/12. 15 eggs retrieved, all mature.
TESE/TESA/aspiration from epididymis, no motile sperm found
froze all eggs, the saga of praying for good sperm continues.
8/3/12: 2nd opinion from MFI uro on biopsy slides. Suspects "partial late maturation arrest."
Plan: more SAs, third biopsy/TESE with frozen back-up either from DH or DS.
SA 8/17/12: Zero sperm
SA 8/23/12: Zero sperm
9/26/12: SPERM FOUND! 15 eggs thawed, 12 survived and were ICSI'd, only 3 fertilized normally. Refrozen as embies and will thaw in Nov. Please survive and grow!
All 3 survived the thaw on 11/15/12!
FET 11/17/12: transferred 2, one 4B, one 4C. Beta 11/30:BFFN
moving on to DS
DIUI#1 2/18/13,50mg Clomid cd 3-7, Ovidrel trigger, Beta 3/4/13: BFN.
DIUI#2 3/19/13, 50 mg Clomid cd 3-7, Ovidrel trigger, Beta #1 (14dpiui) 4/2/13: BFP!!!! 150. Beta #2 4/4/13: 420 Beta #3 4/8/13: 2691. Beta #4 4/15/13: 15,086
1st u/s 4/8/13 shows one gestational sac
2nd u/s 4/15/13 shows yolk sac, fetal pole and early heartbeat
3rd u/s 4/25/13: measuring right on track. Heart rate 148 bpm
A/S 7/22/13: IT'S A BOY!!
PAIF/SAIF Always Welcome
[IMG]http://i49.tinypic.com/2qmon5u.jpg[/IMG] [IMG]http://i225.photobucket.com/albums/dd243/laurakat24/turkeybaster-1.jpg"[/IMG]
Me:34 PCOS, one kinked tube, low thyroid.
DH:39 lower than average count.
Married 2006. 3 failed IUIs and countless BFNs.
~IVF#1: July 2012~
7/10 Retrieval: 16r, 14f w/ICSI. 7/15 ET: Transfered 2. 4 frosties.< Poas faint+ 4dp5dt.>
Beta#1 (8dp5dt): 138. Beta#2 (10dp5dt): 355.
u/s#1: (19dp5dt) 8/3/12 one sac, two yolks! Beta 8,000
u/s#2: two strong heartbeats! EDD 4/2/12
Boy/girl fraternal mono/di twins-- lost our sweet baby girl at 22 weeks due to SIUGR
Preterm labor at 23 weeks 4 days, lost our sweet baby boy.
~*~Married 8/31/08~*~
DX: MFI due to Chemo/Stem Cell Transplant for Hodgkin’s Lymphoma. RE said IVF is best option with DH's frozen boys.
IVF #1 April 2012: Menopur and Bravelle; 1 egg retrieved, 0 fertilized. Boo.
IVF #2 August 2012: Gonal-F 300, Menopur 300. Beta #1 9/6: 382... BFPx2!
Our boys couldn't wait to meet us! Colin and Kieran arrived March 26, 2013 at 33w1d.
Im sorry, BFN's are never easy...and especially when everything is "perfect". I never heard 50% but I know when I had my thaw, they told me they will lose a few cells...and they did 8 cells to 6 cells.
TTC #1 since 3/10:
DX: Me-PCOS, retroverted/ tilted ute - DH- MFI, DH-4 mo of Clomid therapy= no improvement. Weekly HCG injections.
Me-34, DH-33
HSG- unsuccessful, SHSG (dialated)-no blockages
7/11-Clomid (unmonitored) BFN,
#1 Fresh IVF 9/11: w/ ICSI & AH (only option): (1 transfered, 8BF) = BFN!!
#2 FET: 2 transferred (2 6BF) 12/11 = BFFN!!
Surprise + HPT on break! 2/12 Beta 1: 6 Beta 2: <5 = c/p ( RE had given me provera... So pretty sure this ruined everything)<BR> #3 Fresh IVF 3/12: w/ ICSI & AH (2 transfered 8BF & 7BF, 1 to freeze) = BFMFN!
New RE 5/12
6/14 Hysteroscopy
#4 Fresh IVF 8/12: 5dt of 2 5AB blasts = BFN!... what else is new?!?
New RE insists its a transfer issue, immunology checked & good
#5 IVF FET 1/13 under anesthesia : Two 5 day blasts transferred
+ HPT!! Beta1: 2315 Beta2: 6442 Beta3: 31,061
First u/s 1/30/13: Shows 1 healthy heartbeat!!
Was he was right? I wasted 4 IVF's and the doctors were not getting the catheter in?!?
~~ Bump Bestie/ IRL Lynn0926 ~~
IVF #1 in August 2012: BFP!
L was born on May 5, 2013, 8lb. 6oz.
PAIF/SAIF welcome!
Our Project Make A Baby
(((huge hugs))) It is just so unfair...
GL with your FET.
TTC since March 2009 // Me and DH - 28
Testing Summer/Fall 2010 - Unexplained IF
IUIs #1-4 ~ Clomid/Ovidrel/TI/IUI ~ all BFNs
IUI #5 ~ Femara/Ovidrel/TI/IUI ~ BFN
IUIs #6-9 ~ Research Study Meds/Pregnyl/TI/IUI ~ all BFNs
IVF Consultation, More Testing
Diagnostic Cycle ~ Mucinex/Progesterone/TI ~ BFN
IVF #1 ~ Menopur/Bravelle/Ganirelix/Novarel/Progesterone/Lupron
7R, 6F // 2 transferred // 3 frosties ~ BFN
FET #1 ~ Estrace/PIO/Lupron
3 thawed // 2 transferred // 1 lost // no more frosties ~ BFP!!
Beta #1 - 456 // Beta #2 - 1176 // Beta #3 - 2933 // Beta #4 - 6753
EDD: May 16, 2013
Bedrest for SCH // 6w2d through 10w1d
Elevated TSH and Lazy Thyroid DX @ 10w - Started Synthroid
Finally released from RE at 13w
~~ My IF Blog ~~
Ksfrye, I don't have any info re: frosties, but I just wanted to say that so much of what you wrote in this post resonated so deeply. I'm so sorry for this road you have had to walk. It isn't fair at all in so many ways.
That said, I truly admire your strength and will to fight, and want you to know that there are others (like me) who are standing with you, and will be here when you need us. Sending you GIANT hugs, lots of love -- and hope that your frostie is a fighter too, just like you!!
Married June 2007, TTC since May 2010. Me=40, age-related infertility, DOR, low prog, low AMH. DH=37,low morph.
IUI#1 (Dec. 2011)=BFN, IUI#2=unexpected early O=TI=BFN. Official IUI#2=BFN.
IUI#3=3/17/12=BFN.
Stims for IVF#1 started 7/6/12. ER done 7/15/12. ICSI and AH. Transferred 2 embies 7/17/12. Stick little ones, stick! Beta 7/30/12=BFN HcG less than 2.
Surprise BFP while deciding next steps! EDD: 5/10/13
TTC 10/11. IUI 2/12. BFP 3/8/12. 4/26/12 missed mc. RE consult 5/17/12. IVF #1 ER 7/13/12 53R, 41M ICSIed, 32F, 8 5d, 6 6d blasts - all PGD/frozen. PGD results 1 normal M and 1 normal F, 1 maybe M. FET 9/6, transferred 1 F embie. Beta 9/15 BFN. FET#2 planned for 11/2012 put off until 2013. Surprise BFP 11/21/12!! My son was born on 7/24/13!
Nothing to add on the thaw rate - although form readings I did think it was around 90%.
But HUGE hugs coming your way. So sorry about this bad news. Your strength is admirable.
Better days ahead!
"I won't give up on us, even if the skies get rough, I'm giving you all my love, I"m still looking up."
TTC #1 since August 2011 MFI Diagnosis - April 2012
IVF #1 - July 2012 - Stims start 7/2, ER 7/12, 20 retrieved, 16 mature, 13 fertilized!
ET - 7/17 - 1 blast transferred. Beta - 7/26 273, Beta 2 7/30 - 1143. Beta 3 8/6 - 11,597
12/25 - Santa tells us "IT'S A GIRL!" EDD - April 4th
Our Little Easter Bunny has arrived!
Molly Mildred born 03/31/13
TTC A Sibling....... FET #1 11/14/14, Transferred one beautiful blast
Remaining four frosties arrested due to "embryologist error"
Plllllleasssee stick little icicle.....Beta 11/23...BFN
Starting ALL over with a fresh IVF cycle
Stims start 11/28/14, ER December 10th, 13 eggs retrieved, 11 mature, only 4 fertilized
1 Blast Transferred on December 15th..... Beta Christmas Eve... Please Santa, bring me a baby!
Beta #1 345.....Beta #2....750/ First U/S 1/13/15/HB 131....EDD 9/2/2015
Me: 29, Mild DOR
DH: 31, SE mostly normal, 1st SE morph 5%, 2nd SE morph 15%...yeah!.
BFP July 2011, Natural MC August 2011.
3 cycles of 50mg Clomid = BFN
*New RE* Feb/Mar 2012 100 mg Clomid + Trigger + IUI = BFN
*3rd RE* April-June -Break Cycles begin prep for IVF by doing 2 Heparin injects daily....fun fun!
IVF #1 - ER 7/19, ET 7/24, 2 beautiful embies transferred. Beta 8/2 = BFN
*New RE...yes again* FET Nov 2012 with our lone ranger = BFFN
RE Suggests Trying IUI Again, Jan. 2013 IUI #2 =BFN
Feb. 2013 IUI #3 = BFP!!!, Beta #1 (15dpIUI) = 90, Beta #2 (17dpIUI) = 210, U/S Scheduled for 3/18
IUI #1 March: BFN, IUI #2 April: BFN.
IVF #1: Started stims 7/30--CANCELLED.
IVF #1.2: Stims start 10/8/12, ER: 10/20/12; 11R/8M/4F, 5DT: 10/25/12, transfer of a 4AA and 3AB Blast. BFP on HPT 10/31/12; Beta #1: (16 DPO) 954! Beta #2: (18 DPO) 1968! First U/S: TWINS!! A/S: TWO BOYS! EDD: 7/13/13
PAIF/SAIF Always Welcome.
unexplained infertility
4 IUI cycles= CP
IVF #1=18 eggs retrieved, 16 mature and 14 fert. with ICSI ("freeze all" at day 2 OHSS)
FET #1- 2 (day3) embies, BFP
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