Pregnant after IF

Day 3 Tranfer Ladies... can I ask a question?

Hi all, I am very new to the IVF side so I hope you don't mind me asking a question here.  If I'm on the wrong board, please let me know.  I unexpectadly over-stimmed during a TI cycle and we had to convert to IVF.  My ER was on Saturday (25 follicles removed, 18 mature, 8 fertilized) and was told on Sunday that I will be doing a Day 3 transfer.  Everything I have read says that these are not ideal and are generally done early due to embryo quality.  Now of course I am freaking out.

Do we have successful Day 3 transfer ladies here?  Would you mind sharing how many embies you transfered?  We are trying to determine whether or not to transfer 2 at this point. I would prefer to avoid multiples, but don't want to transfer just 1 if the odds are very low to it sticking.  We don't exactly have a huge budget to repeat this.  Ugh, this whole process is so confusing and having only 2 days to absorb and prepare is not helping.  We were so unprepared that I didn't even know that I would be unconscious for the ER. 

Anyway, I do have a call in to my doctor for more info, but of course they are taking their sweet time getting back.  Any advice you could give in the meantime would be appreciated. 

 Our baby boy,Logan, was born still at 19w3d on 7/1/2011
Our 2nd baby boy, Mason, was born still at 20w3d on 1/31/2012

 After a much needed sanity break... we are praying for our rainbows

((BFP 7/29/13))  ((EDD 4/12/14))  It's BOY/GIRL twins!!!

Re: Day 3 Tranfer Ladies... can I ask a question?

  • Studies are inconclusive whether a 3 or 5 day transfer makes a difference.  Pregnancy rates are the same for both.

    I am currently KU, though barely and awaiting my second beta results, from a 3dt.  I transferred 3 embryos, 2 8-cell grade one and 1 7-cell grade one.  My first beta at 13dp3dt or 16dpo was 787.

    We chose to put 3 back due to my age (40).  I don't see your age in your post or sig.  Pregnancy rates for women less than 35 for SET and DET are almost identical.

    HTH. 

    Me - 40, DH 34 Married 11 years, TTC since 7/09 3 rounds of Clomid > Vivienne born 5/28/11
    TTC#2 since 01/13 - 3 rounds of Clomid, 2 IUI w/injectibles, moving to IVF
    IVF #1 - Lupron 20 6/19, Follistim 225 6/21, Menopur 75 6/27, Trigger 6/30
    ER 7/2 (8R, 7M, 5F); ET 7/5 - 2 8 cell, grade 1 and 1 7 cell, grade 1 Stick babies, stick!
    BFP on HPT at 11dp3dt
    Beta #1 13dp3dt 787
    Beta #2 17dp3dt 6,007
    1st u/s 5w2d showing one "good" sac and 2-3 questionable
    2nd u/s 6w2d showing one baby with HR 128bpm
    3rd u/s 7w1d - HR 159bpm - graduated from RE!
    MaternT21 test results: no chromosomal issues, it's a BOY!!!
    EDD March 25, 2014

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  • Ditto what pp said about rates being similar. I did a 3 day transfer both times. The time that stuck transferred a 4 cell,5 cell and ,6 cell due to age and poor Embie quality. One of those little guys stuck and split. Good luck!
    Me (37) DH (39); PCOS changed to Unexplained, changed to DOR in 2012 (finally a correct diagnosis!); 
    Started TTC 2009 with RE after 6 months.  
    Clomid + Trigger x2; 
    IUI + Femara x1,
    IUI + Follistim x2;
    IVF #1 (MDL) February 2013- BFN.
    IVF #2 (antagonist) May 2013, First BFP of my life. 
    Identical twin miracle BOYS (!!) headed our way- due date is technically 2/4/14 but c section is scheduled for 1/7! 


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  • Thanks.  I'm 30 with severe PCOS.  I have no idea what my egg quality is, but she feels that PCOSers don't usually make it to Day 5.  Something about the eggs don't make it. 

    After speaking with her, she thinks we should be aggressive and transfer 2, since most day 3 will end in at least a singleton.  I just am afraid that both will take and/or split and I'll be stucking with a pregnancy that I know I can't handle.

     I give you ladies alot of credit.  This has been one of the most difficult situations I've ever been through.

     Our baby boy,Logan, was born still at 19w3d on 7/1/2011
    Our 2nd baby boy, Mason, was born still at 20w3d on 1/31/2012

     After a much needed sanity break... we are praying for our rainbows

    ((BFP 7/29/13))  ((EDD 4/12/14))  It's BOY/GIRL twins!!!

  • Hi there,

    I am also 30 with PCOS And just underwent my first ivf. Before the er the dr decided he would like to transfer 12 depending on quality if we did a 3 day but would prefer transfering only 1 if it were a 5 day. I know the research at my office shows transferring two 5day blasts does not increase the chance of pregnancy but greatly increases the chance of twins. I'm unsure what the stats are for a three day transfer. If I were in your shoes and completely uncomfortable with the idea of twins I would only transfer one.

    I'm curious as to what your dr said about pcos and not doing a five day transfer. I had 15 eggs retrieved, only 6 mature and 5 fertilized. I was sure we'd be having a three day. Due to high quality of 3 we made it to day 5. We decided to transfer 2 and I find out Friday if we are having twins. The third made it to freeze and the other two did not make it.

    Good luck with your decision! Its a lot to think about in only 2 days!
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  • I had 5 IVF transfers.  Always day 3 transfers for me.  I did get pregnant the first, third and fifth cycles.  The first & third ended in miscarriages.  My fifth only got one egg at retrieval and we transferred that one and I am 28 weeks pregnant... so 3 day transfer do and can produce healthy babies!  Good luck!
    Me 35, DH 36
    TTC summer 2008
    Diagnose me. DOR, DH perfect
    IUI # 1 6/2010, BFN
    IUI # 2 8/2010, BFN
    IVF # 1 10/2010 Canceled poor response
    IVF 1.2 12/2010 BFP! mc 6 weeks 2 days
    Mental health break for 10 months
    IVF # 2 10/2011 BFN
    IVF # 3 5/2012 BFP! 10 eggs retrieved (best ever)
    7 fertilized transferred 3
    Beta #1 14dpo - 72, Beta #2 17dpo 145 Beta 3 20dpo 521
    First u/s June 15 saw HB 126 bpm missed m/c 7/5/12 10 weeks D&C 7/6/12
    IVF#4 ER 9/30 ET 10/3 Beta 10/16 BFFN. IVF #5 final with o/e. ER 1/21 only 1 retrieved, hoping my lonestar is the one. Beta #1 2/6/13 = 209.... please let this be it! Keep growing lonestar! Beta #2 2/8/13 - 586! , Beta #3 2/10/13 = 1898. First u/s perfect little heart beat at 116 bpm. Measure 6 weeks 1 day. EDD 10/14/13
    3/4/13 measuring right on track beautiful heartbeat 171 bpm, graduated from RE to OB... bittersweet.
    PAIF/SAIF always welcome! Its a girl!

    Maggie Grace is here!  10/5/13... 8lbs 6 ounces of pure joy!

    TTC#2  No birth control since DD was born.  Getting ready to jump back in the saddle.  Weaning this month. RE
    appt scheduled 5/8.   Here we go again!



  • We did 3dt both times, our first IVF we transferred one and got a bfn this time around we transferred two and we are 7 weeks with a singleton. This is a very hard decision but I think you need to do what you feel is best. Good luck.
    TTC#2 Since September 2010 with MFI - Me: 36 DH:35
    11/12: IVF ICSI #1 - BFN
    05/13 - Started IVF ICSI #2 - Menupor/Follistim/Trigger
    6/17/13 ER - 7 Retrieved, 6 matured, 4 fertilized
    6/20/13 ET - 2 transferred 0 to freeze
    7/3/13 Beta #1 = 174!  7/7/13 Beta #2 = 414!
    7/15/13 U/S #1 - Can't wait!!


     

  • Hi! We just did our first IVF and transferred 2 embryos on day 3. Both were 8 cell, grade A. I am now pregnant with twins. So, day 3 transfers really can be very successful! You will find there are many women here who have had success with day 3.
    TTC since June, 2011 with anovulatory PCOS, 1 blocked tube, and mild MFI
    3rd cycles clomid + Ovidrel = BFN
    4th cycles letrozole/Ovidrel + IUI = BFN
    IVF #1 = BFP! Twins due 2/5/2014
    Lilypie Pregnancy tickers
  • We did a 3dt and I'm 36 weeks today we transferred 3 embryos and this one was the lucky one that stuck. My siggy has my info. Wishing you the best of luck!!

    Me 38 MH 41 - TTC since June 2010 - dx with Severe MFI. Straight to IVF with ICSI. IVF #1 - ER 06/13/12 - 9 Eggs Retrieved - 4 ICSI'd - only 2 fert. 06/15/12 - 2DT - 3 cell & 6 cell with fragmentation. Beta 06/29/12 - IVF #1 = BFN. 07/20/12 - WTF Appt -Told by our RE to quit IVF. Second Opinion from RE is good. IVF#2 - November 2012. Estradiol Pills Started 11/6. Stims start 11/16. ER 11/26 - 7 eggs retrieved - all mature. 4 fertilized with ICSI. ET 11/29 Transferred 3 embryos. Beta is 12/10. 1st Beta 81 2nd Beta 160 and 3rd beta 360!!! First U/S 12/21/12 - We saw one beautiful gest. sac. 2nd U/S is 01/04/2013 - H/B 183 02/05/13 - NT Scan - everything looks good and IT'S A BOY!  Aiden was born 08/20/2013.

    IVF #2 is in progress.  ER was 05/12/14 - 11 eggs retrieved, 8 fertilized with ICSI.  ET was 05/15/14 - we transferred 3 embryos as we did on the cycle my son was conceived.  We were able to freeze 3 embryos. Beta is scheduled for 05/26/14.  1st beta - 111.  2nd beta - 159 didn't double :( 3rd beta Friday 5/30) - not a lot of hope left. Beta # 3 is 247 - probably ectopic.  Beta # 4 is 813 - possibly vanishing multiple sydrome?  06/05/14 - 5w4days - first U/S - we see a gestational sac and yolk - still have hope!  06/17/14 - 7w1day - U/S and saw and heard the heartbeat - Finally!  06/27/14 - 8w4days - Baby and heartbeat look and sound great :)  EDD 02/01/14 and It's a boy!


     "Everything will be okay in the end. If it's not okay, it's not the end."


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  • image figgs0831:

    Thanks.  I'm 30 with severe PCOS.  I have no idea what my egg quality is, but she feels that PCOSers don't usually make it to Day 5.  Something about the eggs don't make it. 

    After speaking with her, she thinks we should be aggressive and transfer 2, since most day 3 will end in at least a singleton.  I just am afraid that both will take and/or split and I'll be stucking with a pregnancy that I know I can't handle.

     I give you ladies alot of credit.  This has been one of the most difficult situations I've ever been through.

    Lurker here... Um. I think you need to pay more attention to the at least in your bolded statement. I did a 3dt and only put back one. It is now DS. I was shown the rates of success within my age group (35-37) at my clinic with 1 vs 2 embryos transferred on day 3, and I think there was about a 50% chance of twins with a DET on day 3 in successful pregnancies. That is a lot! I wasn't willing to risk it so I opted for 1, even though 2 were suggested. That said, the only reason I was called in for a day 3 transfer is that I only had 6 eggs fertilize out of 10 retrieved, and they weren't sure how many would make it to day 5 since it was my first IVF and I was on the older side. It turns out that 1/6 became DS, and another 3/6 made it to nice looking blasts good enough to freeze on day 5 to 6, so I had a pretty good rate of survival. I am pretty sure I would have twins right now if I had put back 2.

    This is an incredibly hard decision, and I was only comfortable going the SET route once I made sure that I could afford to do IVF more than once. 


    IVF Oct '11 brought us the little man of our dreams on July 29, 2012!

    image
  • Thank you all for your responses.  They were all super helpful.  For some reason, I had a lot of trouble getting on here yesterday, so I appologize for not responding back sooner.

    We had our transfer yesterday afternoon and what an event that was.  A new doctor did my transfer and he did not agree with my doctor's advice on a 3-day transfer.  He did make a good case about being more aggressive and transfering 2, which we ended up doing.  Now I pray that we made the right choice.

    Thank you all again!

     Our baby boy,Logan, was born still at 19w3d on 7/1/2011
    Our 2nd baby boy, Mason, was born still at 20w3d on 1/31/2012

     After a much needed sanity break... we are praying for our rainbows

    ((BFP 7/29/13))  ((EDD 4/12/14))  It's BOY/GIRL twins!!!

  • My 30 year old PCOS eggs were able to handle a 6dt & even ended up with 18 frosties (all day 6)


    04/07/11- PCOS Diagnosis w/GYN. Put on Metformin (1500 mgs)
    04/25/11- 1st consultation with RE (Confirmed PCOS & Anovulation)
    05/09/11-HSG-All clear! 05/13/11-SA-Normal. Found out on 2/14/12, low Morph (1%).
    06/17/11-10 days of Clomid (100, 150) No response.
    07/10/11-03/20/12- 5 Injectable (Follistim) IUI cycles; 4 BFN, 1 C/P. (stims ranged from 11 days to 25 days)
    05/28/12-Diagnosed with Hypothyroidism. 75 mcg Synthroid.

    IVF with ICSI in June/July 2013 = BFP!. Beta # 1 = 123. Beta # 2 = 252. Baby boy arrived March 27, 2013!

    FET #1 - 10/4/14 = BFP!! Beta #1 = 179. Beta # 2 = 499.

    Daisypath Anniversary tickers


    image





  • I did a single embryo transfer of a 3d, and I am 21w with just 1! She stuck around.
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  • Thanks Rachey and Google!  I ended up transfering 2 on Day 3.  Out of all my embies, only 2 made it to freeze.

    Now, I'm 6dp3dt and am freaking out over the 2WW.  I have no symptoms whatsoever and am convinced it has failed.  First betas are Friday 8/2. I caved and took a cheapie test today and it was inconclusive.  There was a shadow of a 2nd line, but I'm not convinced it actually meant anything. 

     Our baby boy,Logan, was born still at 19w3d on 7/1/2011
    Our 2nd baby boy, Mason, was born still at 20w3d on 1/31/2012

     After a much needed sanity break... we are praying for our rainbows

    ((BFP 7/29/13))  ((EDD 4/12/14))  It's BOY/GIRL twins!!!

  • Just remember that 9dpo (which is basically what you are) is SUPER early.  Most women will not see a BFP until around 12dpo (9dp3dt).
    And I have zero symptoms, none.  My last beta was over 6k.  Some women just don't have bad symptoms or they don't show up until later.  Symptoms don't equal KU. :)
    Me - 40, DH 34 Married 11 years, TTC since 7/09 3 rounds of Clomid > Vivienne born 5/28/11
    TTC#2 since 01/13 - 3 rounds of Clomid, 2 IUI w/injectibles, moving to IVF
    IVF #1 - Lupron 20 6/19, Follistim 225 6/21, Menopur 75 6/27, Trigger 6/30
    ER 7/2 (8R, 7M, 5F); ET 7/5 - 2 8 cell, grade 1 and 1 7 cell, grade 1 Stick babies, stick!
    BFP on HPT at 11dp3dt
    Beta #1 13dp3dt 787
    Beta #2 17dp3dt 6,007
    1st u/s 5w2d showing one "good" sac and 2-3 questionable
    2nd u/s 6w2d showing one baby with HR 128bpm
    3rd u/s 7w1d - HR 159bpm - graduated from RE!
    MaternT21 test results: no chromosomal issues, it's a BOY!!!
    EDD March 25, 2014

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