Infertility Veterans

A little anxious (NIFR)

I'm a little anxious because as part of my lab results from my RE, we learned my liver enzymes were a little elevated. My RE wanted me to go to my primary care doctor to figure out why. I saw my pcp this morning and she ordered a whole bunch of new blood work and an ultrasound for tomorrow morning. :( I hardly drink (maybe a glass of wine a week, if that) and I only take Metformin for insulin resistance and a super low dose of Synthroid. I hate new mysteries and I especially hate my body sometimes! Has anyone else dealt with abnormal liver tests?

************ Signature/Ticker Warning ************
Me (32) DH (36) - Finding our way to baby #1
Me: POF/DOR - AMH <0.16, heterozygous c677t MTHFR, insulin resistant and gluten intolerant
DH: Severe MFI

12/2/11 - IUI #1- BFN 
8/1/12 - IVF #1 - Zero response from max stims (600iu intramuscularly)

My ovaries are just for decoration

12/6/12 - Adopted five embryos that had been frozen for over ten years!
2/11/13 - DEmbryo FET #1 Thawed four, sadly two didn't survive. Transferred two beautiful blasts. 
2/16/13 - First BFP of my life @ 6dp5dt! EDD 10/30/13
3/27/13 - After beta and u/s hell, no heartbeat ever detected. D&C at 9w1d.

6/5/13 - Adopted four new embryos that had been frozen for seven years!
 
9/12/13 - DEmbryo FET #2. Thawed and transferred two beautiful blasts
9/17/13 - BFP @ 5dp6dt! EDD 05/31/14
9/29/13 - m/c @ 5w1d. :(

11/19/13 - DEmbryo FET #3. Thawed and transferred one blast from each batch. Wow!
11/23/13 - BFP @ 4dp6dt! EDD 8/7/13
Beta #1 @ 13dp6dt - 522  Beta #2 @ 16dp6dt - 1373 
6w5d ultrasound showed one perfect baby with a beautiful heartbeat of 134bpm!

Snowflake baby is a girl!

Lilypie Pregnancy tickers

    
My embryo adoption blog: Wishing on a Snowflake
 
    image      image 

Re: A little anxious (NIFR)

  • ((Hugs)) I haven't dealt with that before, so I have no advice. However, my acupuncturist has asked me several times if my RE has discussed possible effects on the liver from fertility meds. He said he'd read an article about it but couldn't remember what meds it was discussing. It might be worth researching?

    ***signature & ticker warning***


    Me: 30 ~ Stage IV Endo ~ AMH .38 ~ AFC 8
    AMH .97 as of 4/2012! ~ AMH 1.63 as of 4/2013!?!

    Him: 28 ~ perfect swimmers
    Laparotomy w/partial oophorectomy 8/2009 to remove cysts/endo.
    Stopped BCP 4/2010.
    Multiple clomid rounds from 11/2010 to 6/2011. ~ All BFN
    IUI w/clomid 7/2011. IUI w/clomid & injectables 11/2011 & 1/2012. ~ All BFN
    IVF:EPP 5/2012 ~ (4R, 3M, 2F w/ICSI). Both embryos txfrd. ~ BFN
    BCP to manage endo from 10/2012 to 12/2012.
    FET w/donor embryos #1: 10/2013 Cancelled
    FET w/donor embryos #1.2: 11/2013 ~ ET of 2 beautiful blasts on 11/27.
    Beta 1: 503(12dp5dt) Beta 2: 1035(14dpt) Beta 3: 3001(16dpt)
    Beta 4: 8503(19dpt)
    Twins with an EDD of 8/15/14! Team Purple

    If you're wondering about my avatar...it's a fried pickle chip shaped like a fetus!


    image
  • image DoublePortion:
    ((Hugs)) I haven't dealt with that before, so I have no advice. However, my acupuncturist has asked me several times if my RE has discussed possible effects on the liver from fertility meds. He said he'd read an article about it but couldn't remember what meds it was discussing. It might be worth researching?

    I can only imagine the toll all the meds take on our livers. And mind you, I was only 3 weeks post miscarriage when my blood was drawn. I did read that progesterone itself can cause elevated enzymes, and even the damage done in an IM injection can cause it. But my RE didn't think it was related, and neither did my pcp.

    I forgot to mention that my pcp thought it might be a gall bladder issue. And if it is, I get to have it removed. YIPPEEEEEE. Not.

    ************ Signature/Ticker Warning ************
    Me (32) DH (36) - Finding our way to baby #1
    Me: POF/DOR - AMH <0.16, heterozygous c677t MTHFR, insulin resistant and gluten intolerant
    DH: Severe MFI

    12/2/11 - IUI #1- BFN 
    8/1/12 - IVF #1 - Zero response from max stims (600iu intramuscularly)

    My ovaries are just for decoration

    12/6/12 - Adopted five embryos that had been frozen for over ten years!
    2/11/13 - DEmbryo FET #1 Thawed four, sadly two didn't survive. Transferred two beautiful blasts. 
    2/16/13 - First BFP of my life @ 6dp5dt! EDD 10/30/13
    3/27/13 - After beta and u/s hell, no heartbeat ever detected. D&C at 9w1d.

    6/5/13 - Adopted four new embryos that had been frozen for seven years!
     
    9/12/13 - DEmbryo FET #2. Thawed and transferred two beautiful blasts
    9/17/13 - BFP @ 5dp6dt! EDD 05/31/14
    9/29/13 - m/c @ 5w1d. :(

    11/19/13 - DEmbryo FET #3. Thawed and transferred one blast from each batch. Wow!
    11/23/13 - BFP @ 4dp6dt! EDD 8/7/13
    Beta #1 @ 13dp6dt - 522  Beta #2 @ 16dp6dt - 1373 
    6w5d ultrasound showed one perfect baby with a beautiful heartbeat of 134bpm!

    Snowflake baby is a girl!

    Lilypie Pregnancy tickers

        
    My embryo adoption blog: Wishing on a Snowflake
     
        image      image 
  • Yes!  All the time, unfortunately.  It's becoming more common I think too.  For me, I was diagnosed with Focal Nodular Hyperplasia and non-alcoholic fatty liver disease.  Honestly, I think my liver enzyme are mostly affected by what I eat.  The first time I had them tested they were horrible, 6 months later they were much better but still abnormal.  I ate a lot better in those 6 months.  Then another 6 months later, after eating horribly, they came back the worst ever!

    Try not to worry about it too much until you know something.  I will tell you one thing though.  I freaked out when they "found and saw something" on the ultrasound.  Then they wanted me to have an MRI and then I saw a liver specialist.  I was diagnosed with FNH and it's essentially benign liver masses.  Mine have gotten a little smaller each year since stopping birth control pills but they still are concerned about it growing with the increased estrogen.

    FWIW though, my friend has it, went through IF treatments, got pg and has a child now and no issues with her liver and still has the same stupid elevated enzymes.

    ETA: I'm being put strictly on progesterone for supression instead of bcp because it isn't metabolized through the liver.

    TTC #1 Since May 2011 ~ Everyone Welcome ~  Our Journey Together As One

    See Details Here

    M
    E(30): DOR due to chemo and radiation @ age 7, FNH of liver, Hypothyroid
    DH(30): MFI due to testicular torsion and removal @ age 13, Low testosterone


    January 2014 ~ IVF/ICSI & PGS ~ no response to stims ~ converted to IUI ~ BFN


    February 2014 ~ On to donor embyros
    Profile selected ~ 5 blasts!!! 

    3
    /18 ~ FET #1 ~ Transferred 2 blasts ~ BFN
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    image
  • sorry you are dealing with this. metformin can cause slightly elevated ALT. have they tested your liver enzymes before (and after being on metformin)?

    it may be your "normal" on metformin. liver is nothing you want to lose, so it is better if they are cautious.

    (((hugs))) 

    TTC #1 since 12/2010 DH: MFI, cancer survivor Me: Resected septate uterus, lap treated mild endo, tubes open, ovulate on own, autoimmune disease 3 Failed IUI's (2/2012, 4/2012, 6/2012) 
    IVF #1 August 2012. BFP! Beta #1 56.7 Beta #2 150 One baby, one heartbeat on 9/20/12! no h/b @7w6d. dandc @8w0d
    FET #1 December 2012, BFN
    FET #2 February 2013, no embies survived thaw
    IVF #2, BFP #2, Loss #2 March 2013, Scar tissue discovered, RPL testing,
    IVF #3, BFP #3, Loss #3 (twins) September 2013
    Hostile ute, moving onto Gestational Carrier!

    GC/FET #1 of 1 5AA blast and 1 compacted blast, February 2014, BFP #4 on 3/1/2014!
    6w u/s 1 bean with h/b of 145 bpm, 8w u/s 187 bpm
    EDD 11/7/14. Please, please, please stick little one!

    Praying unceasingly for a miracle. ALL welcome!

    image










  • Hope it doesn't end up being a problem for you.
    Married 8/2008. IVF with PGD March 2013.
    3/22 ER: 25R, 20M, 15F. 9 genetically normal, and 3 survived to Day 5
    3/27 ET: transferred 1 embryo, beta 9dp5dt=163, 12dp5dt=639
    4/25 1st ultrasound at 7 weeks = identical twins with heartbeats?!!!
    PPROM at 31w, delivery at 32 weeks of two beautiful girls
    image
  • No advice. Just hugs!

    Countless BFN(s)
    Moving to IVF

    IVF1 (ICSI): Long Lupron
    6R. 3F. 3DT. 8Cell 1Grade 2Embies. 1Frostie.
    Beta 1/22: 14 Beta 1/24: 24 Beta 1/26: 28
    Round One Result: Chemical Pregnancy

    Pressing Forward

    IVF2 (ICSI/AH/ACU): Microdose Lupron Flare
    13R. 11F. 5DT. 2TFR'ed. 1Frostie.
    Round Two Result 4/30: Harsh BFN

    FET. 2TFR'ed.
    Round Three Result 6/25: BFN
    Where do we go from here?

    Moving forward with CCRM in 2013
    ODWU revealed blocked tube(s). Lap 2/15.
    Bilateral Tubal Ligation. Stage IV Endo.
    Finally some (tough) answers.


    IVF3 (ICSI/CCS): Antagonist with EPP
    13R. We have 3 CCS Normal Embryos!


    Lupron Depot: May 2013 to August 2013
    Long awaited FET on 9/3. 2TFR'ed.
    BFP on FRER 5dp5dt: IN SHOCK!
    Beta1 9/10: 152.7! Beta2 9/12: 378! Beta3 9/14: 1224! 

    1st ultrasound 10/1: TWO beautiful heartbeats!  Overjoyed!

  • DH had this. It was all diet related. He changed his diet and lost some weight and his numbers are now normal. Hopefully utcus an easy fix for you. Sorry you have to deal with this.
    TTC 1/2010 DH Dx - Azoospermia 2/2011
    Hysteroscopy 3/2011 2 Polyps removed 4/2011
    DH on Clomid / Arimidex to address hormonal issues - Sperm found July 2011!
    IVF #1 September 2011 - ER 9/8/2011- 8R, 5M - icsi - 1 made it to transfer - BFFN :-(
    IVF #2 Lucky November 2011 - ER 11/25/2011 - 15 eggs!, 13 mature, 10 fertilized with isci - 7 made it to transfer! Transferred 1 - 8 cell and 2 - 7 cell. BFP!!!!
    1st U/S - Twins! 2nd U/S - 3 heartbeats!!! - HOLY COW!!!
    Prayers for our take home babies!
    2 babies born on 3/27/12 and lost. Last baby born on 3/29/12 and lost at 20 weeks.
    My angels grew wings shortly after birth.
    Ahava Raisel, Matisyahu Nissim & Zev Chaim - Mommy and Daddy will always love you.
    IVF #3 July 2012 - ER 7/17/2012 - 10 R. 5 F. 4 made it to ET
    Transferred 2 on 7/20/2012 no snow babies :-(
    Beta on 7/31/2012 = BFMFN
    A miracle gift expected to come to us through adoption around 9/2012
    Baby girl adopted - Birth Mother changed her mind and took the baby back
    IVF #4 October 2012 - New RE. Doing PGD Testing. 8 R, 7F, 2 made it to 5 day blast for PDG testing. Both Normal (Thank you G-d!!!) 1 boy and 1 girl
    transferred one beautiful 5day blast (girl)
    Please G-d the almighty one - let this be our take home baby!
    Beta #1 158, Beta #2 318, 1 Absolutely magnificent HB at 175! Thank you G-d!!!
    Baby Girl born August 5th. Thank you G-d for our precious miracle.
    AMA. PAIF & SAIF always welcome - I need all the prayers I can get!

    Lilypie Angel and Memorial tickers
  • Sending positive thoughts your way.  I hope it is nothing.  ((Hugs))

     
    me 33/DH 36
    ttc since 10/2008; d/x: mild MFI, stageII endo
    ~~PAIF/SAIF Welcome~~
    11 IUI’s = 1 m/c (7w4d)
    IVF#1 January 2012 BFN, FET #1 April 2012 BFN
    Surprise BFP October 2012 m/c (7w), Surprise BFP April 2013 m/c (6w4d)
    IVF #2: July 2013, ET 1 embryo 7/18, beta 1 @ 14dp3dt - 757, beta 2 @ 16dp3dt - 1762
    U/S 1 @ 6w4d = 1 little frogger with HB of 118, U/S 2 @ 7w3d measuring right on track with HB of 160
    Stick Frogger Stick! Please!!!!!!!!!!!!!   It's a Girl, EDD April 7, 2014

    BabyFruit Ticker

  • Thank you all so much.

    ************ Signature/Ticker Warning ************
    Me (32) DH (36) - Finding our way to baby #1
    Me: POF/DOR - AMH <0.16, heterozygous c677t MTHFR, insulin resistant and gluten intolerant
    DH: Severe MFI

    12/2/11 - IUI #1- BFN 
    8/1/12 - IVF #1 - Zero response from max stims (600iu intramuscularly)

    My ovaries are just for decoration

    12/6/12 - Adopted five embryos that had been frozen for over ten years!
    2/11/13 - DEmbryo FET #1 Thawed four, sadly two didn't survive. Transferred two beautiful blasts. 
    2/16/13 - First BFP of my life @ 6dp5dt! EDD 10/30/13
    3/27/13 - After beta and u/s hell, no heartbeat ever detected. D&C at 9w1d.

    6/5/13 - Adopted four new embryos that had been frozen for seven years!
     
    9/12/13 - DEmbryo FET #2. Thawed and transferred two beautiful blasts
    9/17/13 - BFP @ 5dp6dt! EDD 05/31/14
    9/29/13 - m/c @ 5w1d. :(

    11/19/13 - DEmbryo FET #3. Thawed and transferred one blast from each batch. Wow!
    11/23/13 - BFP @ 4dp6dt! EDD 8/7/13
    Beta #1 @ 13dp6dt - 522  Beta #2 @ 16dp6dt - 1373 
    6w5d ultrasound showed one perfect baby with a beautiful heartbeat of 134bpm!

    Snowflake baby is a girl!

    Lilypie Pregnancy tickers

        
    My embryo adoption blog: Wishing on a Snowflake
     
        image      image 
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