I have my LO on Zantec now. It seems to help with the burning but only for so long. I know it is not supposed to reduce the amount of spit up but it is possible that prilosec does. I know they say that spit up is a laundry problem as long as she is not in any pain, but it is so excessive! Any mom's out there have their LO on zantec and switched to prilosec? Did the prilosec help with the burn and reduce the amount of spit up?