Trying to Get Pregnant

Anyone else on Clomid..?

This is my first round of Clomid I started at 50mg and I took my last pill yesterday! YAY!! I did experience some moodiness and anxiety from the medication so that wasn't great, but it will be all worth it in the end if it can help my chances of conception. 

I am feeling hopeful for this cycle and I was just curious if anyone else was on it and how their experience was/is!

Thanks :) 

«1

Re: Anyone else on Clomid..?

  • image Slapptastic:
    How are you being monitored?


    This is my question as well.
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  • My doctor has me coming in getting BW done on certain days and she has been giving me pelvic exams every time I go in and see her. But other than that nothing else
  • image Slapptastic:
    How are you being monitored?

    This. I find myself more, and more surprised with the amount of women given this medication like its Advil without proper previous testing and cycle monitoring... 

    ETA~ has your SO been tested too? Male infertility is just as common. 

    Mama of 1: who did not grow below my heart, but certainly a big place in it!!



    TTC our #1 since '10


    DX: Ovulate but not great follicles


    DH SA:Normal-Low Count


    Aug 2012:Clomid 50MG= BFFN ([1]Fol-17mm/Prog.-17.3)


    Sep 2012: Clomid 150MG CD5-9 & TI= ??



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  • image Bella521:
    My doctor has me coming in getting BW done on certain days and she has been giving me pelvic exams every time I go in and see her. But other than that nothing else


    You should be having ultrasounds? Is this your OB or an RE?
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  • image angelamaster1986:

    image Slapptastic:
    How are you being monitored?

    This. I find myself more, and more surprised with the amount of women given this medication like its Advil without proper previous testing and cycle monitoring... 

    I had all my BW done prior to being put on Clomid and DH's SA came back with great results. We also had been having unprotected sex for three years and been trying for a year before talking to my doctor. I think it's safe to say she did not hand it out like Advil.

    She even sent more tests to be run on my thyroid because even though it was in "normal" range she wanted to check for antibodies. She has been very cautious and thorough during this whole process. I feel very comfortable with what she is doing. Thanks for your concern though!

  • image Bella521:
    image angelamaster1986:

    image Slapptastic:
    How are you being monitored?

    This. I find myself more, and more surprised with the amount of women given this medication like its Advil without proper previous testing and cycle monitoring... 

    I had all my BW done prior to being put on Clomid and DH's SA came back with great results. We also had been having unprotected sex for three years and been trying for a year before talking to my doctor. I think it's safe to say she did not hand it out like Advil.

    She even sent more tests to be run on my thyroid because even though it was in "normal" range she wanted to check for antibodies. She has been very cautious and thorough during this whole process. I feel very comfortable with what she is doing. Thanks for your concern though!

    Many OB's do hand it out like Advil, and most patients that don't know will just take it w/o the proper diagnostic testing and/or monitoring. Did you have an HSG? You should be having CD3 bloodwork and u/s and mid cycle u/s, and then bloodwork on 7DPO (not CD21)

    Me: Total Thyroidectomy    DH: Varicocele 
    TTC#1 since 5/11 - BFP 1/13  - LO Born 9/13

      


  • image Bella521:
    My doctor has me coming in getting BW done on certain days and she has been giving me pelvic exams every time I go in and see her. But other than that nothing else

    .....a pelvic exam or an ultrasound? The only reason people get concerned is many doctors don't do the proper monitoring with clomid, and it can lead to a lot of problems. Speaking from personal experience. 

    PCOS Dx 12.08 / BFP! 4.22.10 DS1 born 1.4.11 DS2 born 6.19.13
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  • image Bella521:
    image angelamaster1986:

    image Slapptastic:
    How are you being monitored?

    This. I find myself more, and more surprised with the amount of women given this medication like its Advil without proper previous testing and cycle monitoring... 

    I had all my BW done prior to being put on Clomid and DH's SA came back with great results. We also had been having unprotected sex for three years and been trying for a year before talking to my doctor. I think it's safe to say she did not hand it out like Advil.

    She even sent more tests to be run on my thyroid because even though it was in "normal" range she wanted to check for antibodies. She has been very cautious and thorough during this whole process. I feel very comfortable with what she is doing. Thanks for your concern though!



    Just for reference. Answer if all of this has been done prior to using Clomid?

    "Before starting Clomid you need to make sure there is no male
    infertility, no ovarian cysts, and that FSH and liver functions are
    normal.

    The following tests should be done before Clomid is given:

    Sperm count
    Estrogen levels
    CD 3 FSH levels
    Thyroid function tests
    Prolactin levels
    Liver function tests
    Endometrial biopsy"

    Yes or no? You are putting your health in jeopardy if you are not properly monitored before and during treatment.

    Just thought you should know. Good luck.


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  • Yes, all of it has been done other than the HSG which she said she would rather do after a few rounds of Clomid
  • image Bella521:
    Yes, all of it has been done other than the HSG which she said she would rather do after a few rounds of Clomid

    You only have a lifetime max of 6 rounds of Clomid, I hope you don't have any blockage in your tubes and you are wasting cycles. 

    Me: Total Thyroidectomy    DH: Varicocele 
    TTC#1 since 5/11 - BFP 1/13  - LO Born 9/13

      


  • image Bella521:
    image angelamaster1986:

    image Slapptastic:
    How are you being monitored?

    This. I find myself more, and more surprised with the amount of women given this medication like its Advil without proper previous testing and cycle monitoring... 

    I had all my BW done prior to being put on Clomid and DH's SA came back with great results. We also had been having unprotected sex for three years and been trying for a year before talking to my doctor. I think it's safe to say she did not hand it out like Advil.

    She even sent more tests to be run on my thyroid because even though it was in "normal" range she wanted to check for antibodies. She has been very cautious and thorough during this whole process. I feel very comfortable with what she is doing. Thanks for your concern though!

    Oh this is good to hear! I wish you luck. I was on 50 last month. The results are in my siggy. This month, I was boosted up to 150. I have an u/s on Fri to see how we are doing. 

     

    ETA~I requested an HSG on my first medicated cycle because I was freaked by the idea there could be a blockage and Id be wasting time, money, and putting my body through it.

    Mama of 1: who did not grow below my heart, but certainly a big place in it!!



    TTC our #1 since '10


    DX: Ovulate but not great follicles


    DH SA:Normal-Low Count


    Aug 2012:Clomid 50MG= BFFN ([1]Fol-17mm/Prog.-17.3)


    Sep 2012: Clomid 150MG CD5-9 & TI= ??



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  • image Bella521:
    Yes, all of it has been done other than the HSG which she said she would rather do after a few rounds of Clomid

    Great! I would push for an HSG as well, only because you have a limited number of cycles you can take clomid and if you find out you had a blockage later it would suck. You can always do it during a treatment cycle.

    Good luck! I hope it works for you.

    PCOS Dx 12.08 / BFP! 4.22.10 DS1 born 1.4.11 DS2 born 6.19.13
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  • image SweetC80:

    image Bella521:
    Yes, all of it has been done other than the HSG which she said she would rather do after a few rounds of Clomid

    You only have a lifetime max of 6 rounds of Clomid, I hope you don't have any blockage in your tubes and you are wasting cycles. 

    Actually, I asked my RE about this because she said she wanted to continue Clomid with me. I explained to her that I have already taken Clomid 4 times and according to everything I've heard, I only have 2 cycles left to do this. She said that while it is true, nothing necessarily happens if you take it more than 6 times. Obviously, if it's not working after 6 cycles, you need to try something different and that's our plan, but I found it interesting that some RE's do not believe in the lifetime max of 6 rounds of Clomid. To the OP, I also started on 50mg of Clomid and had the same side effects you're experiencing. I O'd, but it did not ultimately get me pregnant. Hopefully you have better luck!

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  • Thanks for all the support ladies!! I can only wish for the best, and I'll keep everyone updated!!
  • My RE would NOT give clomid until an HSG was done. If your tubes happen to be blocked, the clomid would be a waste. But it sounds like other than that, you have had the necessary testing. You definitely need ultrasound monitoring during clomid cycles, as well. I am starting round 5 this coming cycle. Good luck!
    TTC#2 Since July 2011
    Me: 29, had two blocked tubes - left was cleared during lap, right was unable to be cleared. PCOS & Stage 2 Endo. DH: 32, SA = perfect
    CLOMID: 4 rounds, 50mg + TI = BFN's. FEMARA: 1 round = no response
    12-24-2012 : Laparoscopy, Softball sized cyst/endo/scar tissue removed.
    Cycle #14 - Feb 2013 : 50mg clomid. Ovidrel Trigger. IUI on 2/14/13 = thin lining, multiple cysts.
    Cycle #15 - no meds, still have cysts, no follicles. Boo!
    Forced break. Continuous BCP for 6 weeks to give my jacked up ovaries a break.
    Cycle #16 actively trying (May/June): Femara, TI = BFN
    Cycle #17- #20 - Med/Treatment break, trying on our own = BFN's all around.
    Cycle #21 - Femara, MORE Femara, Ovidrel and a Christmas IUI = BFN
    MY BLOG -- About DD, TTC and everything in between!

    image
  • image MrsP821:
    image SweetC80:

    image Bella521:
    Yes, all of it has been done other than the HSG which she said she would rather do after a few rounds of Clomid

    You only have a lifetime max of 6 rounds of Clomid, I hope you don't have any blockage in your tubes and you are wasting cycles. 

    Actually, I asked my RE about this because she said she wanted to continue Clomid with me. I explained to her that I have already taken Clomid 4 times and according to everything I've heard, I only have 2 cycles left to do this. She said that while it is true, nothing necessarily happens if you take it more than 6 times. Obviously, if it's not working after 6 cycles, you need to try something different and that's our plan, but I found it interesting that some RE's do not believe in the lifetime max of 6 rounds of Clomid. To the OP, I also started on 50mg of Clomid and had the same side effects you're experiencing. I O'd, but it did not ultimately get me pregnant. Hopefully you have better luck!

    Mine goes by the same theory. Said the 6 cycle 'myth' came from one study that studied ovarian cancer. A certain percentage of a certain group of women in that study had ovarian cancer and had taken x amount of clomid in their lifetime.  


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  • image PrimRoseMama:

    Endometrial biopsy

    I have never heard this as a pretest for Clomid. 

    Now, your list is missing HSG.  Is that maybe what they meant to put on this list?

    OP - I'm really glad you had full testing/monitoring for your Clomid cycle.  I think you've taken all the questions very well (instead, like some posters, getting all huffy that you were asked a bunch of questions).  We do get a lot of people on here that have NO clue how 'real' Clomid is and pop it like tic tacs.  I am very happy you are not one of them.

    To answer your original question - I did 50mg of Clomid CD3-7 this month.  Unfortunately, I did not respond.  At all.  BUT - I also haven't ovulated in over 9 months.  My doc switched me to the highest dose (5mg) Femara next cycle.


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    CFNBC Since 8/2011 - ALL Welcome

    Lupus/MCTD (2009); Hashimotos (2012); Endo (2012); 

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  • image bbg676:

    image PrimRoseMama:

    Endometrial biopsy

    I have never heard this as a pretest for Clomid. 

    Now, your list is missing HSG.  Is that maybe what they meant to put on this list?

    OP - I'm really glad you had full testing/monitoring for your Clomid cycle.  I think you've taken all the questions very well (instead, like some posters, getting all huffy that you were asked a bunch of questions).  We do get a lot of people on here that have NO clue how 'real' Clomid is and pop it like tic tacs.  I am very happy you are not one of them.

    To answer your original question - I did 50mg of Clomid CD3-7 this month.  Unfortunately, I did not respond.  At all.  BUT - I also haven't ovulated in over 9 months.  My doc switched me to the highest dose (5mg) Femara next cycle.

    I really hope that it works for you!! I never would have imagined it being so much work to get pregnant lol but I guess I will be able to appreciate it that much more. I do O on my own right now and have regular cycles so I'm hoping that could be working in my favor. We shall see! I will check in to see how it worked for you bbg :) GL

  • image KaramelSutra:
    image MrsP821:
    image SweetC80:

    image Bella521:
    Yes, all of it has been done other than the HSG which she said she would rather do after a few rounds of Clomid

    You only have a lifetime max of 6 rounds of Clomid, I hope you don't have any blockage in your tubes and you are wasting cycles. 

    Actually, I asked my RE about this because she said she wanted to continue Clomid with me. I explained to her that I have already taken Clomid 4 times and according to everything I've heard, I only have 2 cycles left to do this. She said that while it is true, nothing necessarily happens if you take it more than 6 times. Obviously, if it's not working after 6 cycles, you need to try something different and that's our plan, but I found it interesting that some RE's do not believe in the lifetime max of 6 rounds of Clomid. To the OP, I also started on 50mg of Clomid and had the same side effects you're experiencing. I O'd, but it did not ultimately get me pregnant. Hopefully you have better luck!

    Mine goes by the same theory. Said the 6 cycle 'myth' came from one study that studied ovarian cancer. A certain percentage of a certain group of women in that study had ovarian cancer and had taken x amount of clomid in their lifetime.  

    While I am no expert in reproductive health I have had more than one doctor tell me that the more rounds of ovary stimulating medicine does start to raise your risk of Ovarian cancer and if you are already at risk, increases your risk even more. I am fairly certain that a standard medical practice isn't used because of one study and/or a myth.

    Me: Total Thyroidectomy    DH: Varicocele 
    TTC#1 since 5/11 - BFP 1/13  - LO Born 9/13

      


  • image SweetC80:
    image KaramelSutra:
    image MrsP821:
    image SweetC80:

    image Bella521:
    Yes, all of it has been done other than the HSG which she said she would rather do after a few rounds of Clomid

    You only have a lifetime max of 6 rounds of Clomid, I hope you don't have any blockage in your tubes and you are wasting cycles. 

    Actually, I asked my RE about this because she said she wanted to continue Clomid with me. I explained to her that I have already taken Clomid 4 times and according to everything I've heard, I only have 2 cycles left to do this. She said that while it is true, nothing necessarily happens if you take it more than 6 times. Obviously, if it's not working after 6 cycles, you need to try something different and that's our plan, but I found it interesting that some RE's do not believe in the lifetime max of 6 rounds of Clomid. To the OP, I also started on 50mg of Clomid and had the same side effects you're experiencing. I O'd, but it did not ultimately get me pregnant. Hopefully you have better luck!

    Mine goes by the same theory. Said the 6 cycle 'myth' came from one study that studied ovarian cancer. A certain percentage of a certain group of women in that study had ovarian cancer and had taken x amount of clomid in their lifetime.  

    While I am no expert in reproductive health I have had more than one doctor tell me that the more rounds of ovary stimulating medicine does start to raise your risk of Ovarian cancer and if you are already at risk, increases your risk even more. I am fairly certain that a standard medical practice isn't used because of one study and/or a myth.

    Sweet - my RE at the University also said that it used to be believed it led to ovarian cancer, but in the last year two different studies came out that showed there really is no risk.  She showed both of them to me (and they were peer-reviewed and in journals, too, I believe).  I wish I would have written down what they were titled.  I'll try to find them some time.

    That said, we still decided to only ever do 6 cycles.  And that was a bust because on the first cycle my vision started acting up.

    Also - when I did some research after she showed me the studies, the main reason on legit sites (aka not message boards) for stopping after 6 cycles is that each cycle has less of a chance of working.  By the time you hit your sixth cycle, the benefits start to fade and the risk increase (including thinning of the lining). 

    From what I read, the chance of becoming pregnant during the 7th or later cycle of Clomid is much lower than the first cycle.  It just makes more sense to switch it up and try something new at that point.


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    CFNBC Since 8/2011 - ALL Welcome

    Lupus/MCTD (2009); Hashimotos (2012); Endo (2012); 

    Complete Anovulation; Low Prog & E + High T & DHEA
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    BFP #2 - 2/4/2013 EDD 10/20/2013 M/C 2/11/13 

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  • image bbg676:

    Sweet - my RE at the University also said that it used to be believed it led to ovarian cancer, but in the last year two different studies came out that showed there really is no risk.  She showed both of them to me (and they were peer-reviewed and in journals, too, I believe).  I wish I would have written down what they were titled.  I'll try to find them some time.

    That said, we still decided to only ever do 6 cycles.  And that was a bust because on the first cycle my vision started acting up.

    Also - when I did some research after she showed me the studies, the main reason on legit sites (aka not message boards) for stopping after 6 cycles is that each cycle has less of a chance of working.  By the time you hit your sixth cycle, the benefits start to fade and the risk increase (including thinning of the lining). 

    From what I read, the chance of becoming pregnant during the 7th or later cycle of Clomid is much lower than the first cycle.  It just makes more sense to switch it up and try something new at that point.

    I can only tell you that my doctors told me specifically that it was for risk of Ovarian cancer. Obviously it isn't a standard belief across the board on either side, and there are studies to support both beliefs. Who knows currently which is correct. I already have a higher risk of ovarian/breast cancer, and I am not willing to take that risk.

    Me: Total Thyroidectomy    DH: Varicocele 
    TTC#1 since 5/11 - BFP 1/13  - LO Born 9/13

      


  • image bbg676:
    image SweetC80:
    image KaramelSutra:
    image MrsP821:
    image SweetC80:

    image Bella521:
    Yes, all of it has been done other than the HSG which she said she would rather do after a few rounds of Clomid

    You only have a lifetime max of 6 rounds of Clomid, I hope you don't have any blockage in your tubes and you are wasting cycles. 

    Actually, I asked my RE about this because she said she wanted to continue Clomid with me. I explained to her that I have already taken Clomid 4 times and according to everything I've heard, I only have 2 cycles left to do this. She said that while it is true, nothing necessarily happens if you take it more than 6 times. Obviously, if it's not working after 6 cycles, you need to try something different and that's our plan, but I found it interesting that some RE's do not believe in the lifetime max of 6 rounds of Clomid. To the OP, I also started on 50mg of Clomid and had the same side effects you're experiencing. I O'd, but it did not ultimately get me pregnant. Hopefully you have better luck!

    Mine goes by the same theory. Said the 6 cycle 'myth' came from one study that studied ovarian cancer. A certain percentage of a certain group of women in that study had ovarian cancer and had taken x amount of clomid in their lifetime.  

    While I am no expert in reproductive health I have had more than one doctor tell me that the more rounds of ovary stimulating medicine does start to raise your risk of Ovarian cancer and if you are already at risk, increases your risk even more. I am fairly certain that a standard medical practice isn't used because of one study and/or a myth.

    Sweet - my RE at the University also said that it used to be believed it led to ovarian cancer, but in the last year two different studies came out that showed there really is no risk.  She showed both of them to me (and they were peer-reviewed and in journals, too, I believe).  I wish I would have written down what they were titled.  I'll try to find them some time.

    That said, we still decided to only ever do 6 cycles.  And that was a bust because on the first cycle my vision started acting up.

    Also - when I did some research after she showed me the studies, the main reason on legit sites (aka not message boards) for stopping after 6 cycles is that each cycle has less of a chance of working.  By the time you hit your sixth cycle, the benefits start to fade and the risk increase (including thinning of the lining). 

    From what I read, the chance of becoming pregnant during the 7th or later cycle of Clomid is much lower than the first cycle.  It just makes more sense to switch it up and try something new at that point.

    My post was getting long so I quoted instead of edited to add this:

    http://www.nytimes.com/2009/02/06/health/research/06cancer.html

    "Fertility Drugs and Ovarian Cancer Not Linked, Study Says" (headline)

    and

    http://www.cancer.org/Cancer/OvarianCancer/OverviewGuide/ovarian-cancer-overview-what-causes

    states, in their risk of ovarian cancer, "Fertility drugs: Some studies have found that use of the fertility drug clomiphene citrate (Clomid?) for longer than one year, especially if no pregnancy took place, may increase the risk of low malignant potential tumors. But not having children also increases the risk, even without the use of fertility drugs. Research in this area is now going on. If you are taking this drug, you should talk to your doctor about the possible risks."

    http://www.mcghealth.org/infertility/GhsuContentPage.aspx?nd=1214

    Studies have shown different results but, Clomid most likely does not increase risk of developing ovarian cancer

    http://www.health.ny.gov/diseases/cancer/ovarian/ov_cancer.htm

    AND - as PP said... even the government admits it was, "One study suggests that women who have taken the fertility drug clomiphene citrate (Clomid) may have an increased risk of ovarian cancer". 

    Other, more studied causes of breast cancer?

    "A family history of ovarian cancer: Having a relative with ovarian cancer increases a woman's risk of getting it herself. Generally, the closer the relative, the greater the risk. However, only about 10% of all ovarian cancers can be linked to a family history of the disease.

    Breast cancer: Women who have had breast cancer are twice as likely to develop ovarian cancer.

    No pregnancies: Women who have not been pregnant are more likely to develop ovarian cancer."

    Lastly:

    "Ovarian cancer has been infrequently reported in patients who have received fertility drugs. Infertility is a primary risk factor for ovarian cancer; however, epidemiology data suggest that prolonged use of clomiphene may increase the risk of a borderline or invasive ovarian tumor."

    http://dailymed.nlm.nih.gov/dailymed/archives/fdaDrugInfo.cfm?archiveid=7613

    There is an established link of infertility/not having children and ovarian cancer.  Only one study has shown a slight increase in Clomid use and ovarian tumors (not even necessarily cancerous, btw).  Isn't it possible that those that had said tumors used Clomid, never got KU, and thus got ovarian cancer more from "infertility" (known contributor) than from the casual link to Clomid use?


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    CFNBC Since 8/2011 - ALL Welcome

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    Complete Anovulation; Low Prog & E + High T & DHEA
    BFP #1 - 11/17/2012 EDD 7/25/2013 M/C 11/19/2012 @ 4w5d

    BFP #2 - 2/4/2013 EDD 10/20/2013 M/C 2/11/13 

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  • image bbg676:

    image PrimRoseMama:

    Endometrial biopsy

    I have never heard this as a pretest for Clomid. 

    Now, your list is missing HSG.  Is that maybe what they meant to put on this list?

    OP - I'm really glad you had full testing/monitoring for your Clomid cycle.  I think you've taken all the questions very well (instead, like some posters, getting all huffy that you were asked a bunch of questions).  We do get a lot of people on here that have NO clue how 'real' Clomid is and pop it like tic tacs.  I am very happy you are not one of them.

    To answer your original question - I did 50mg of Clomid CD3-7 this month.  Unfortunately, I did not respond.  At all.  BUT - I also haven't ovulated in over 9 months.  My doc switched me to the highest dose (5mg) Femara next cycle.

    I didn't respond to Clomid on 50 and 100mg and barely at 150mg so I was switched to 7.5 mg Femara (so 5mg is not the highest dose). 

    OP, I agree that you have had the proper testing before starting Clomid but you need to be seen for a mid-cycle u/s to see how you are responding or if you would need to cancel for too many follicles.  CD21 b/w (which should be done at 7dpo) is not enough.  You would also need to have a baseline u/s and b/w done on CD3 to check for cysts that could have resulted from taking Clomid. 

    Married 9/19/09
    Me (28) Dx PCOS, DH (28) SA = Normal

    Started TTC#1 11/2009
    3 rounds of Clomid + TI and 3 rounds of 7.5 mg Femara + IUI before our BFP on 11/8/10 at 12dpiui
    Beta #1 14dpiui: 104! Beta #2 16dpiui: 230!
    dx Gestational Diabetes at 28 weeks
    RC born at 37w1d due to pre-e

    TTC #2 Aug 2012 Femara 5mg+Ovidrel+TI = no response. Upped dose to 7.5mg for 5 more days = 3 mature follies = c/p :(
    Sep 2012 Femara 7.5mg+Ovidrel+TI = 4 follies = BFP on 10/12/12 at 9dpo
    Beta #1 12dpo = 91, Beta #2 14dpo = 175
    1st u/s 11/1/12 = one baby and saw the hb!
    dx Gestational Diabetes at 14 weeks
    PS born at 39w

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  • image SweetC80:
    image bbg676:

    Sweet - my RE at the University also said that it used to be believed it led to ovarian cancer, but in the last year two different studies came out that showed there really is no risk.  She showed both of them to me (and they were peer-reviewed and in journals, too, I believe).  I wish I would have written down what they were titled.  I'll try to find them some time.

    That said, we still decided to only ever do 6 cycles.  And that was a bust because on the first cycle my vision started acting up.

    Also - when I did some research after she showed me the studies, the main reason on legit sites (aka not message boards) for stopping after 6 cycles is that each cycle has less of a chance of working.  By the time you hit your sixth cycle, the benefits start to fade and the risk increase (including thinning of the lining). 

    From what I read, the chance of becoming pregnant during the 7th or later cycle of Clomid is much lower than the first cycle.  It just makes more sense to switch it up and try something new at that point.

    I can only tell you that my doctors told me specifically that it was for risk of Ovarian cancer. Obviously it isn't a standard belief across the board on either side, and there are studies to support both beliefs. Who knows currently which is correct. I already have a higher risk of ovarian/breast cancer, and I am not willing to take that risk.

    See - that makes total sense.  From what I was reading (and the links I provided), having the genes or family histor of breast or ovarian cancer already makes your risk of getting ovarian cancer higher.  I totally get not wanting to risk it. 

    In fact, I have a really high risk of getting colon cancer (biodad died from it, as did his sister, and two step-siblings have already be dx'd), and I didn't realize (until doing said reaserch) that I, too, am at increased risk for ovarian cancer.  Guess I'm glad I'm no longer taking Clomid. 

    P.S. Wasn't trying to be argumentative earlier.  I just see everyone always talking about the "ovarian cancer risk" with Clomid and never any actual facts/studies/sites to back it up.  Just wanted to provide links on the other side of the issue, because clearly in the medical community it is not just cut and dry.  Smile


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    CFNBC Since 8/2011 - ALL Welcome

    Lupus/MCTD (2009); Hashimotos (2012); Endo (2012); 

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  • image Sarafuss:
    image bbg676:

    image PrimRoseMama:

    Endometrial biopsy

    I have never heard this as a pretest for Clomid. 

    Now, your list is missing HSG.  Is that maybe what they meant to put on this list?

    OP - I'm really glad you had full testing/monitoring for your Clomid cycle.  I think you've taken all the questions very well (instead, like some posters, getting all huffy that you were asked a bunch of questions).  We do get a lot of people on here that have NO clue how 'real' Clomid is and pop it like tic tacs.  I am very happy you are not one of them.

    To answer your original question - I did 50mg of Clomid CD3-7 this month.  Unfortunately, I did not respond.  At all.  BUT - I also haven't ovulated in over 9 months.  My doc switched me to the highest dose (5mg) Femara next cycle.

    I didn't respond to Clomid at all so I was switched to 7.5 mg Femara (so 5 is not the highest dose). 

    OP, I agree that you have had the proper testing before starting Clomid but you need to be seen for a mid-cycle u/s to see how you are responding or if you would need to cancel for too many follicles.  CD21 b/w (which should be done at 7dpo) is not enough.  You would also need to have a baseline u/s and b/w done on CD3 to check for cysts that could have resulted from taking Clomid. 

    That is great to know!  My RE said "the highest dose" but I freaked a bit because I fear I am not going to respond to that dose either.  And then where would I be?  Hopefully she's willing to increase it if need be.  Smile


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    CFNBC Since 8/2011 - ALL Welcome

    Lupus/MCTD (2009); Hashimotos (2012); Endo (2012); 

    Complete Anovulation; Low Prog & E + High T & DHEA
    BFP #1 - 11/17/2012 EDD 7/25/2013 M/C 11/19/2012 @ 4w5d

    BFP #2 - 2/4/2013 EDD 10/20/2013 M/C 2/11/13 

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  • image SweetC80:

    image Bella521:
    Yes, all of it has been done other than the HSG which she said she would rather do after a few rounds of Clomid

    You only have a lifetime max of 6 rounds of Clomid, I hope you don't have any blockage in your tubes and you are wasting cycles. 

    Exactly. My OB did the HSG as the first step before any meds. No reason to take them if it's all blocked up.  


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  • image bbg676:
    image Sarafuss:
    image bbg676:

    image PrimRoseMama:

    Endometrial biopsy

    I have never heard this as a pretest for Clomid. 

    Now, your list is missing HSG.  Is that maybe what they meant to put on this list?

    OP - I'm really glad you had full testing/monitoring for your Clomid cycle.  I think you've taken all the questions very well (instead, like some posters, getting all huffy that you were asked a bunch of questions).  We do get a lot of people on here that have NO clue how 'real' Clomid is and pop it like tic tacs.  I am very happy you are not one of them.

    To answer your original question - I did 50mg of Clomid CD3-7 this month.  Unfortunately, I did not respond.  At all.  BUT - I also haven't ovulated in over 9 months.  My doc switched me to the highest dose (5mg) Femara next cycle.

    I didn't respond to Clomid at all so I was switched to 7.5 mg Femara (so 5 is not the highest dose). 

    OP, I agree that you have had the proper testing before starting Clomid but you need to be seen for a mid-cycle u/s to see how you are responding or if you would need to cancel for too many follicles.  CD21 b/w (which should be done at 7dpo) is not enough.  You would also need to have a baseline u/s and b/w done on CD3 to check for cysts that could have resulted from taking Clomid. 

    That is great to know!  My RE said "the highest dose" but I freaked a bit because I fear I am not going to respond to that dose either.  And then where would I be?  Hopefully she's willing to increase it if need be.  Smile

    That may be the highest dose that she is comfortable prescribing.  But that would surprise me since I've seen a lot of women take 7.5mg (the equivalent to 150mg of Clomid).  Hopefully 5mg does the trick for you! 

    Married 9/19/09
    Me (28) Dx PCOS, DH (28) SA = Normal

    Started TTC#1 11/2009
    3 rounds of Clomid + TI and 3 rounds of 7.5 mg Femara + IUI before our BFP on 11/8/10 at 12dpiui
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    TTC #2 Aug 2012 Femara 5mg+Ovidrel+TI = no response. Upped dose to 7.5mg for 5 more days = 3 mature follies = c/p :(
    Sep 2012 Femara 7.5mg+Ovidrel+TI = 4 follies = BFP on 10/12/12 at 9dpo
    Beta #1 12dpo = 91, Beta #2 14dpo = 175
    1st u/s 11/1/12 = one baby and saw the hb!
    dx Gestational Diabetes at 14 weeks
    PS born at 39w

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  • image bbg676:

    Want to have a throwdown? image jk love.

    Them a lot of words you put in there. I am sure there are a number of studies that say one thing or another. It seems like it could be infertility or the use of drugs or not having children, there are a number of things that can effect your hormones and risk for Ovarian cancer.  I don't have time to do my own google searches, but I just find it odd that if there were study after study saying absolutely 100% that Ovary stimulating drugs do not have an effect on Ovarian cancer and only one that supports the theory then why do so many doctors prescribe to the idea that it does?

    Like I said, I have 2 doctors who told me not just not to do more than 6 cycles on Clomid, but that it increased my risk of Ovarian cancer. I am not willing to take that risk.

    Even w/ all that aside, the OP should have an HSG before taking Clomid, it still isn't candy and for whatever the reason it is not recommended to be taken indefinitely, so if her tubes are blocked she is wasting time and cycles.

     

    Me: Total Thyroidectomy    DH: Varicocele 
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  • image SweetC80:
    image KaramelSutra:
    image MrsP821:
    image SweetC80:

    image Bella521:
    Yes, all of it has been done other than the HSG which she said she would rather do after a few rounds of Clomid

    You only have a lifetime max of 6 rounds of Clomid, I hope you don't have any blockage in your tubes and you are wasting cycles. 

    Actually, I asked my RE about this because she said she wanted to continue Clomid with me. I explained to her that I have already taken Clomid 4 times and according to everything I've heard, I only have 2 cycles left to do this. She said that while it is true, nothing necessarily happens if you take it more than 6 times. Obviously, if it's not working after 6 cycles, you need to try something different and that's our plan, but I found it interesting that some RE's do not believe in the lifetime max of 6 rounds of Clomid. To the OP, I also started on 50mg of Clomid and had the same side effects you're experiencing. I O'd, but it did not ultimately get me pregnant. Hopefully you have better luck!

    Mine goes by the same theory. Said the 6 cycle 'myth' came from one study that studied ovarian cancer. A certain percentage of a certain group of women in that study had ovarian cancer and had taken x amount of clomid in their lifetime.  

    While I am no expert in reproductive health I have had more than one doctor tell me that the more rounds of ovary stimulating medicine does start to raise your risk of Ovarian cancer and if you are already at risk, increases your risk even more. I am fairly certain that a standard medical practice isn't used because of one study and/or a myth.

    This and My RE also mentioned that Clomid thins out your uterine lining which would put you at risk for miscarriage if taken more than 6 cycles. 

    *** TTC since 10/2010 (no planned bc since 2007) Me (31) Sept 2012 - DX Luteal Phase Defect. HSG 8/2012: both tubes are open, cervix and lining look good; hypothyroidism; DH (35) SA Normal Clomid 50mg, trigger
    10/2012 BFFN 1st cycle on clomid 50mg w/trigger shot, progesterone level 19.7, cd28 - hcg level 0.
    ***12/2012 Cycle #25 TTA break until March 2013***
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    OB/GYN=expertise in pregnancy/labor; RE=expertise in getting pregnant. (read this on someone's post, feel free to PM me to give you credit) I'm so glad I have a RE on my team. Consult a RE after 1 year under 35yo; 6 months 35yo+
  • image deelopi9:

    This and My RE also mentioned that Clomid thins out your uterine lining which would put you at risk for miscarriage if taken more than 6 cycles. 

    I have seen users have thin linings after one go, and I myself, (who is currently on cycle 6(7), my lining is perfect. So. Six in one hand, half dozen in the other I guess.

    When I say 6(7), on my 5th round, I didn't respond at 50 (my first dose post baby) so my doc piggy backed on it with 150mg. My lining was 15. So. I will trust my RE group.  


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    2mo: 18lbs 15oz, 25.5 inches <> 4mo: 26lbs 8oz, 27.5 inches6mo: 29lbs 8oz, 30 inches <> 9mo: 32lbs, 32 inches12 mo: 37lbs, 34.5 inches <> 15 mo: 38lbs 6 oz, 36 inches. 20.5 inch noggin18 mo: 43lbs, 37.75 inches 21 inch head2yr: 47 lbs, 42 inches. 21.5 inch head. Woah.  

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