Does anyone have A1298c MTHFR homozygous mutation?

Mauilovespink

I just found out that I have the homozygous A1298c MTHFR mutation.  I have had 2 pregnancy losses.  The first was a possible, but never confirmed, ectopic.  Second was a 4 1/2 week natural miscarriage or chemical pregnancy.  (sac never seen)  I also a few family members with Factor IV leiden or some varient, so my OB wanted me to get tested for that and other disorders since I had back to back losses.  I am negative for Factor IV, thankfully.  But, I do have the MTHFR mutation.  My OB suggests I see a Genetic Counselor about this.  Does anyone else here have this mutation?  Are you on any meds?  Did you see a Genetic counselor?  I have been searching google (bad me!) and not found any good answers.  Thanks for your time!

montvamj

I have MTHFR from one of my parents.  I also have Factor II.  I still don't understand much about it.  I only learned that I had this when my sister found out about it when she was ttc.  At that point, I had already had my first son.  With my second DS I had to give myself injections of blood-thinners.

lavril

I think there are some women on TTCAL that have this.  You may want to post this question there.

damabo80

**badge warning**

 

Scout05 on PGAL is homo A1298C and has a lot of good info about it and her course of treatment. You can page her there or on TTCAL6+.