Trouble TTC
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Femara and Menopur IUI Cycle

My wife and I are in the "Trouble Trying to Conceive" category for sure! Our first strike against us is the lack of sperm in our same sex relationship. That is an easy (yet expensive) fix! Now on to the hard part! 

There have been many ups and downs fertility wise over the past few years. We are lucky to have two female reproductive organs in this family. Only trouble is, we can't get a baby in either one of them! We have had an IVF cycle where eggs did not survive, hysteroscopy with a polypectomy, strange conversations about how to buy sperm, etc... but the worst of all is that period every month. So after a few years break, my wife is up for it again!

Here is what we are looking at: 34 years old, previously unable to ovulate on her own, was given hormones and injectables last go around to get things back on track and eggs died after egg retrieval... two years later hormone levels are in the normal range (but low) and we are going for an IUI this time. Taking Femara days 3-7 and then Menopur 7-9. Will go back for an ultrasound on day 12 to check progress and hopefully be ready for a trigger shot and IUI after that.

Anyone have any advice or similar situations? Any side effects we should look for with either medicine?

Re: Femara and Menopur IUI Cycle

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    I find the meds cause mood swings but other than that I've done fine on them. Best of luck to you.
    **Losses Mentioned**
    Me 41, DH 38 
    TTC #1 since 9/2014 AMH 3.68, FSH 6.6
    IUI#1 12-02-2015 Letrozol, Gonal-F, Pregnyl, Acupuncture, BFP 12-17-2015 beta 1=72, beta 2=64, beta 3=10 MC 12-20-14 
    IUI#2 01-08-2015 Letrozol, Gonal-F, Pregnyl, Acupuncture, BFP 01-23-2015 beta 1=151, beta 2=450, beta 3=6524, beta 4= 29380 u/s at 7w5d baby with heartbeat measuring 6w2d. u/s 2-24 gestational sac only, beta 59400 MC 2-24-15 @ 8w6d D&C 2-27-15. Pathology results 47XX +20

    Diagnosis AMA and compound heterozygous MTHFR
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    Femara makes me have horrible headaches and trouble sleeping. They usually last until about 2 days after I finish my meds. I haven't taken Menopur yet. Good luck!
    Married: 12/15/2012    TTC: 08/2014
    Husband: 26 SA: normal
    Me: 23 Low AMH and damaged ovaries due to chemotherapy.
    No AF or O in 3 years. HSG showed a slight T shaped uterus.

    High Risk OB 9/29- got the ok to get pregnant.
    RE Appt:  10/28/ U/S showed follicles, but also small damaged ovaries.
    B/W results CD0: all normal except low AMH at 1.3
    Cycle 1-November (TI)- Femera 2.5mg, 2mg Estradoil, and Trigger=BFN
    Cycle 2-December (TI)- Femera 2.5 mg ,4mg Estradoil, and Trigger= No O
    Cycle 3-January (TI)- Femera 5 mg, 2mg Estra
    doil, and Trigger=


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    I too have suffered terrible headaches from the stimming meds.  I had issues with bruising if I gave them in my legs, so I stuck to my abdomen.  
    ********Warning BFPs and Losses Mentioned*********
    ME-38 DH-39  DX: DOR  TTC since Nov 2011.
    5/6/13 IUI#1 BFN
    6/3/13 IUI#2 BFN
    7/3/13 IUI#3 BFN
    8/813 IUI#4 cancelled bc no stim
    Referred to IVF
    IVF #1 9/25 start Stims
    10/10 ER 7 Mature Eggs
    10/11 Fertilization Report-nothing fertilized so a rescue ICSI performed.  4 eggs were fertilized.  
    10/13 3 embryos transferred on 3 days(7 cell, 5 cell and 4 cell)
    10/25 Beta BFN
    IVF #2 Start Stims Feb 2014
    2/7 ER 14 Embies...9 Fertilized
    2/12 ET 2 excellent grade.  2 frosties
    2/21/2014 First BFP EVER....ELATED
    3/28/2014 Miscarried.  DNC performed that day. 8w6d
    6/20/2014 FET 2 frosties.  
    6/30/2014 SO HAPPY...BFP #2
    7/21/2014 First u/s.  Low heart rate. Scheduled 2nd u/s in 1 week. 6weeks
    7/28/2014 U/S #2...no heartrate.  Scheduled DNC for 8/1/2014 7weeks
    2/15/2015 IVF #3  E2 Protocol ER 12 eggs retrieved.  ICSI'd 9.  
    2/20/2015 2 transferred. None to freeze.  
    03/2/2015 Beta 4 - CP 
    4/2015 IVF #4 E2 Protocal
    4/19/2015 ER 13R, 11M, 10F w/ICSI
    4/24/2015 ET 2 blasts none to freeze
    5/4/2015 Beta 1 108 
    5/6/2015 Beta 2 225



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