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Infertility Drugs for IUI...make you crazy?

Hello Ladies:

My fiance and I are thinking of starting our first IUI cycle in two weeks. My concern is that my parents will be visiting during this time and I don't want to be a crazy and emotional mess during their trip. What drugs did you take during your IUI treatments and has anyone not have any emotional sides effects? I believe I will start on Clomid, but I'm not sure what the trigger drug will be at this time. 

Any advice would be great!

Me: 33, DH: 32

TTC: 2 years
Fertility blood tests all normal
Tilted uterus
3 day ultrasound 17 follicles
HSG: 11/13/13- tubes open
DH SA: SUPER sperm (145 million, 84% motility, 22% morphology)
All infection disease and immunity blood tests NORMAL

FIRST IUI May 2014: 100 mg Clomid days 5-9, third ultrasound CD 13 revealed four follicles 27, 24 and 20 and 13mm. Trigger shot May 28 with IUI May 29 and 30 (fingers crossed) - BFN started spotting 11DPO :(

IUI #2 B2B 6/23 and 6/24, three mature eggs and 130 million sperm! FX this is the month!  BFN 7/8

3rd cycle benched due to cysts - TI with OPK tests -  BFN

3rd mediated cycle: Clomid+Trigger+TI  (three follies left side, one on right as usual....what the hell right ovary get it together and produce some damn follicles!) 7DPO progesterone level 43 with NO suppositories YAY for a natural strong ovulation. Beta canceled started spotting 13DPO - Third time is not a CHARM! 14 day cycle WTF! Everything looks normal - RE wants to start injectables next cycle so this cycle I'm benched

Officially benched until March....but still plan on trying the baking soda douche due to my excessive and thick CM

JANUARY SIGGY CHALLENGE...This is so me!

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Love this man....he was so before his time in his thoughts and ideas about the world....been obsessed about him lately bringing it back to the early 90s.

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Never thought I would like long hair....

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Re: Infertility Drugs for IUI...make you crazy?

  • Options
    I'm on Gonal, novarel trigger, and progesterone and it does make me emotional. I did have family staying and I was fine around them. They probably would have never known if they didn't catch me injecting meds in my stomach.

    Fucking bump!!!!
  • Options
    I just took 100mg of clomid for the first time and had zero side effects .Good luck!
    BabyFruit Ticker'>*
    TTC #1 since January 2012  Dx: Unexplained infertility & hypothyroidism 
    8/13 BFP!    EDD:  April 25, 2014
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    jencity9jencity9 member
    edited April 2014
    I take Letrozole and progesterone. Both made me moody but it was similar to PMSing or just being slightly irritable. Nothing that would prevent me from spending time with family, and they probably didn't/wouldn't notice.

    Me: 32  DH: 33  Married: March 2004

    July 2006: started TTC
    2008: HSG (normal), couple rounds of clomid through gyno
    2008 - 2010: dragging my feet out of fear and procrastination
    October 2010: first consultation with RE, dx PCOS and fibroids (DH slightly low count/motility)
    Oct. 2010 - Dec. 2012:  In DENIAL! avoided the issue because I was scared of surgery
    January 2013: returned to RE, fibroids grew significantly
    February 2013: second HSG, fibroids pushed on tubes which blocked them somewhat
    March 2013: MRI to determine what type of surgery may be necessary

    July 29, 2013: fibroids (5) removed via robotic laparascopy
    August 2013 - Nov 2013 : benched due to recent surgery

    IUI #1, Dec. 24, 2013, BFN 
    IUI #2, Jan. 25, 2014, BFN
    IUI #3, Feb. 25, 2014  BFN
    IUI #4 canceled due to lack of response to letrozole
    IUI #4.1 April 28, 2014, BFN

    May 16, 2014: wtf consult, start prepping for IVF in June and add injects for one last IUI in the meantime
    IUI #5 started letrozole and bravelle but canceled after HSG led to new diagnosis

    May 21, 2014: third HSG, tubes blocked, one at the beginning, one hydrosalpinx??
    June 11, 2014: consult, approved to move on to IVF because the hydro is not completely blocked therefore allowing fluid to move through slowly rather than backwards
    IVF #1 August 8, 2014 - 3dt of 2 embryos, BFN
    September 17, 2014 - 4th HSG, the right tube is very patent (open!!) dye went straight through this time. Weird!
    October 2, 2014 - started metformin treatment
    November 14, 2014 - blood work, brought A1C down from 5.8 to 5.5

    November 26, 2014 - RE finally back from vaca and reviewed my chart, no more IVFs for rest of calendar year
    December 1, 2014 - Right after Thanksgiving, I called a new clinic and got in right away! Plan for IVF
    December 17, 2014 - ER! 29 retrieved (!!), 16 mature, all 16 fertilized (ICSI)

    IVF #2 December 20, 2014 - 3dt of 3 embryos, BFN

    We are done with treatment unsuccessfully. :(


    PAIF/SAIF/All Welcome!

    image    image
  • Options
    I've only been on injects. I've heard more negative stories than positive with the side effects of Clomid. But everyone is different, so it's hard to say! Good luck!
    Me: 38     DH: 36
    Married: July 21, 2013
    TTC#1 (between us): June/July 2013

    DX: MFI (low count and motility)
    Charting/OPK/CBFM July 2013-present
    1st RE Visit: January 2014
    Cycling: 
    March 2014- 75iu follistim + trigger + progesterone + IUI = BFN and OHSS
    (8 million post wash 47% motility, 18mm/17mm/16mm/16mm/14mm follies)
    April/May 2014- Benched due to cysts/enlarged ovaries
    June 2014- 50iu follistim + trigger + progesterone + IUI = BFP!!
    (10 million post wash 60% motility, 20mm/19mm follies)
    Beta 1- 85 Beta 2- 2,752 - EDD 2/27/2015


    Everyone welcome. Strength in numbers!


  • Options
    I've only used follistim, ovidrel, and progesterone. I experienced zero side effects from the follistim and ovidrel but I HATE progesterone

    4 Losses (2003, 2008, Apr 2012, & Oct 2012)
    All RPL and IF testing with multiple REs = normal

    5 IUIs = BFN

    All AL are welcome
    Image and video hosting by TinyPic

  • Options
    You would probably be ok in terms of the drugs. People differ, but I took my Clomid at night and mostly I just had terrible night sweats. I was therefore tired and somewhat emotional during the day, but nothing that would prevent me from being around family. I think the thing I might be worried about is getting bad news (not responding or over-responded and having my cycle cancelled) and having to "hold it together" if the people staying with me didn't know what was going on.

    I think that depends if your family knows what you're going through, what point in your cycle you are in (the first couple of days of Clomid would almost definitely be fine, the end of Clomid/beginning of monitoring might be harder), and your general relationship with your family (do they get under your skin under normal circumstances).
    **siggy warning**  **everyone welcome**

    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    DS- 11.07.02
    DSS- 6.26.04
    Married- 6.29.13
    TTC Again- Sept. 2013
    ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
    Test Results/Diagnosis- HSG & SA totally normal
    DX: 3/2014 Prolactinoma/Hyperprolactinemia- Started cabergoline 2/2014
    5/2014 Possible mild PCOS in addition to hyperprolactinemia??
    7/2014 Adding probable tubal factor to the diagnosis list
    9/2014 And now adding hypothyroid to the list- Started synthroid 9/2014
    Cycles 1-4 - Sept.-March- All Anovulatory 
    IUI #1 March/April-  Clomid 50mg + Clomid 100mg +Trigger + IUI #1 = BFN
     IUI #2 April/May-Clomid 100mg + Clomid 150mg + Trigger + IUI #2 + Endometrin=BFN
    IUI #3- June- Follistim 75iu + Trigger + IUI #3  Benched due to a 40 mm cyst. :-(
    IUI #3- July- Follistim 75iu + Trigger + IUI #3 + Endometrin = BFP! on 7/25/14
    Slowly rising betas - Ectopic suspected on 8/8/14 & confirmed on 8/11/14
    Methotrexate on 8/12/14 -HCG negative on 9/2/14
    IVF #1- November- Antagonist protocol: 11/1: start stims, 200iu of Follistim; 11/12 ER 17R/14M/14F; 11/17 5 day transfer of two blasts, 2 blasts and 2 expanding morulas frozen; 11/22 BFP!! (On FRER at 5dp5dt)
    Betas: 9dp5dt 205, 11dp5dt 497, 14dp5dt 1,709
    u/s at 5w0d- 1 sac; u/s at 6w0d 1 baby with heartbeat, another sac without a heartbeat
    image


  • Options
    Clomid was awful for me, I was miserable on it. Emotionally I was more sad, crying than mean and irritable, so I'd take it even if I had family staying. Having family over May even help your mood sine it'd have your mind on other things.
    *** SIGGY WARNING ***

    Happily Married Since 10.2006  •  TTC since 07.2012
    HSG Good & SA mostly Normal  •  DX lean PCOS
    MAR - NOV 2013  •  5 Cycles Clomid + TI = 2 Late O's/BFN & 3 Big Fat FAILS
    DEC 2013 - FEB 2014  •  IUI #1-3  •  Femara 5mg + Trigger = 3 BFNs
    MAR 2014  •  IUI #4  •  Follistim + Trigger + Crinone = BFN
    APR 2014  •  Benched  •  BCPs to clear up Cysts

    MAY 2014  •  IUI #5  •  Follistim + Ganirelix + Trigger = BFP
    E.D.D. 2/18/2015
    6/11 +HPT • 6/13 BETA 447 • 6/16 BETA 1535
    6/23 U/S Adorable Little Bean • 6/30 U/S Beautiful Strong Heartbeat

    image

  • Options
    I asked the same question that you're asking prior to starting my IUI.  I was so worried because I had heard horror stories about fertility medicines.  Don't do too much research because I believe that you can psych yourself out to have some of the symptoms.

    I took clomid, ovidrel and progesterone. 

    Clomid = No side effects for me.
    Ovidrel = No side effects for me.
    Progesterone inserts = That's a whole different story.

    Just remember that everyone responds to medicines differently.  You may have no side effects from any of the medicines.   Good luck!
    Married on October 20, 2012.  Began trying in January 2013.
    RE appointment & testing December 2013 - February 2014= Unexplained IF, possible endometriosis
    IUI#1- March 22 (100mg clomid, 75 mg of Bravelle, Ovidrel trigger) = BFP!!!



  • Options
    Thanks everyone for your input. My family is unaware we are seeing an RE and that we are seeking treatment, so that was my main concern with showing the side effects during their stay.

    Thanks again for all the replies!

    Me: 33, DH: 32

    TTC: 2 years
    Fertility blood tests all normal
    Tilted uterus
    3 day ultrasound 17 follicles
    HSG: 11/13/13- tubes open
    DH SA: SUPER sperm (145 million, 84% motility, 22% morphology)
    All infection disease and immunity blood tests NORMAL

    FIRST IUI May 2014: 100 mg Clomid days 5-9, third ultrasound CD 13 revealed four follicles 27, 24 and 20 and 13mm. Trigger shot May 28 with IUI May 29 and 30 (fingers crossed) - BFN started spotting 11DPO :(

    IUI #2 B2B 6/23 and 6/24, three mature eggs and 130 million sperm! FX this is the month!  BFN 7/8

    3rd cycle benched due to cysts - TI with OPK tests -  BFN

    3rd mediated cycle: Clomid+Trigger+TI  (three follies left side, one on right as usual....what the hell right ovary get it together and produce some damn follicles!) 7DPO progesterone level 43 with NO suppositories YAY for a natural strong ovulation. Beta canceled started spotting 13DPO - Third time is not a CHARM! 14 day cycle WTF! Everything looks normal - RE wants to start injectables next cycle so this cycle I'm benched

    Officially benched until March....but still plan on trying the baking soda douche due to my excessive and thick CM

    JANUARY SIGGY CHALLENGE...This is so me!

    image


    Love this man....he was so before his time in his thoughts and ideas about the world....been obsessed about him lately bringing it back to the early 90s.

    image

    Never thought I would like long hair....

    image

  • Options
    This cycle I was on Clomid + HCG trigger shot.  Emotionally I was a little affected but nothing out of control.  I think I would have been fine if I had anyone to entertain around that time.  One crazy side effect (not sure if anyone else has experienced this) with Clomid for me though was VIVID DREAMS!  I'm CD17 now (took Clomid CD3-7) and I'm still experiencing them.  I dream in color.  I remember such vivid detail like people's faces and smells of different foods that I was eating in the dream.  Very weird for sure.  I don't mind that side effect, it was kind of interesting actually!  ;)  
    **Formerly EastBayBride508**

    Me 34   Him 33

    Me - Left salpingo-oophorectomy at 19 due to large cyst/torsion  and 2 large uterine fibroids found at age 30
    Him - Borderline low sperm count (correcting through Fertility Blend supplement)

    Married 8/20/2011
    TTC #1 since Jan 2013
    First appointment with RE 10/2013.  
    April 2014 - Clomid 100mg CD3-7.  HCG shot CD10 IUI #1 done on 4/12/14 (CD12) ....BFN
    May 2014 - Break cycle to repeat saline sonogram and re-group.  Travel to Kauai 5/7-5/12 (Yay!!)
    June 2014 - Clomid 150mg CD4-8.  HCG shot CD14.  IUI#2 done on 6/9 and 6/10 (CD15-16) w/ Prometrium suppositories during TWW .... BFN
    July 2014 - Clomid 150mg CD3-7.  Ultrasound CD12 - 4 mature follies! HCG trigger shot CD12 AM.  IUI#3 on CD13 w/ Prometrium suppositories during TWW ....BFN
    July 2014 - Repeat ultrasound done to measure size of fibroid - 8x9cm (the size of a grapefruit!) Surgery referral made.
    August 2014 - MRI done which revealed 2 fibroids: a 13x15cm fibroid as well as an 8x7cm one.  Super freak out mode over surgery plan.  OB-GYN/surgeon said surgery would most likely have to be a laparotomy (open abdominal surgery)
    August 2014 - After a 2nd opinion, plan to take Lupron x 2 months to shrink fibroids then laparoscopic/robotic myomectomy.  Surgery date is set for Nov 21st!  
    November 2014 - Robotic myomectomy done (2 large fibroids removed, mild endo found).  Benched x 3 months

    PAIF/SAIF welcome
  • Options
    Clomid made me an absolute mess. I was either bitchy or I was crying. Or I was clinging on to DH like a sad lost puppy. And I felt miserable all the time.  WORST 7 days of my life both times. The second cycle was a teeny bit better, I was more under control but then I got the worst headache I can imagine. 

    Lilypie Angel and Memorial tickers

    TTC: Started May 2012
    Bloodwork - potential ovulation issue which seemed to be fixed by clomid.
    SA - Mot (36%) and count low 9.3 mil (updated) 
    HSG - Oct 16 2013 - came back clear
    Clomid #1 - Nov. 2013 - BFN
    BFP#1 =  Clomid #2, Dec. 2013 - EDD 9.9.14 Loss Jan 9
    Femara #1 + Trigger (2/21) Feb. 2014 +ruptured ovarian cyst - BFN
    SIS clear
    April 2014: 50IU Follistim CD3-CD9 + 25IU CD10-CD13+CD13 trigger 1 mature follie= BFN
    IUI #1: May 2014 50IU Follistim + trigger + IUI = BFN
    IUI #2: June 2014 50IU Follistim + IUI (3 mil sperm)=  BFN
    TI #2: June 2014 50IU Follistim  + Trigger = BFN
    BFP#2 = IUI# 3: Aug 2014 75IU Follistim+ Trigger + IUI (2 mil sperm) EDD May 15

    BabyFruit Ticker


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     Love bugs unite!
    Daisypath Anniversary tickers

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